起订量:
BPS Bioscience的蛋白酶筛选和检测服务
中级会员第2年
生产厂家BPS Bioscience专注于开发高质量的产品,提供优质的客户服务,并维护稳健的质量管理体系。BPS Bioscience现已通过ISO 9001:2015认证,确保质量的持续监控和持续改进,从而满足客户需求。
BPS Bioscience产品涉及临床前药物开发过程的每个阶段。其中部分产品可以用于许多研究阶段。BPS Bioscience将继续丰富我们的产品线,希望以此推动了整个早期药物研发过程。
BPS Bioscience
BPS Bioscience的蛋白酶筛选和检测服务
Accelerate your drug discovery program with Protease Screening and Profiling Services from BPS Bioscience, Inc. Trust us to provide you with high quality data with fast turnaround time. Our team of experts along with our broad services portfolio makes it easy to:
Screen for inhibitors/targets using our panel of many different assays including Cathepsins, Caspases, Dipeptidyl Peptidases (DPPs), Deubiquitinases, and other Proteases
Select from IC50 determination and single point concentrations
Receive data within days of compound submission
Perform follow-up studies using the same proteins manufactured in-house
Get questions answered or project guidance in a time-efficient manner
Aspartic Proteases | Cysteine Proteases | Metalloproteases | Serine Proteases |
---|---|---|---|
BACE1 | SARS-CoV-1 3C-like Protease (3CL) | ADAM17 | CLP |
Caspase-3 | SARS-CoV-2 3C-like Protease (3CL) | MMP1 | DPP3 |
Caspase-6 | SARS-CoV-2 Papain-like Protease (PLPro) | MMP2 | DPP4 |
Caspase-7 | A20 | MMP3 | DPP7 |
Caspase-8 | Ataxin-3 | MMP7 | DPP8 |
Caspase-9 | Cathepsin B | MMP8 | DPP9 |
Renin, activated | Cathepsin F | MMP9 (Q279R) | FAP |
Cathepsin L | MMP10 | Furin | |
Cathepsin S | MMP11 | HCV1a (D168V) | |
Cathepsin V | MMP12 | HCV1b | |
MALT1 | MMP13 | HCV1b (D168V) | |
OTUD6Bc | MMP14 | HCV1b (R155K) | |
UCHL1 | HCV1b (R155Q) | ||
UCHL3 | HCV2a | ||
USP2 | POP | ||
USP5 | Protein C, activated | ||
USP7 | TMPRSS2 | ||
USP8 | |||
USP10 | |||
USP14 |
Note: Not all targets will have a commercially available reference control. Please inquire with our team if you need to furnish your own controls for specific targets.
Protease signaling pathways regulate a wide range of vital physiological processes, including digestion of food, lysosome and proteasome degradation, apoptosis, blood coagulation, and cell cycle regulation.
The dysregulation of protease activity can lead to pathologies such as arthritis and inflammatory diseases,cardiovascular disorders, cancer, osteoporosis, Alzheimer’s, and other neurological disorders. Several small molecule, protease inhibitor drugs are already on the market and many more are in development.
如果您需要了解更多关于我们的服务的信息,请联系info。