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Anti-phospho-APS(Ser598) 磷酸化APS抗体
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生产厂家上海雅吉生物科技有限公司生产/代理进口原装/分装抗体 :Anti-phospho-APS(Ser598) 磷酸化APS抗体
英文名称 Anti-phospho-APS(Ser598)
中文名称 磷酸化APS抗体
产品类型 一抗 磷酸化抗体
抗体来源 Rabbit
克隆号 Polyclonal
交叉反应 Rb
蛋白分子量 Predicted Molecular Weight: 68KDa
性状 Lyophilized or Liquid
浓度 1mg/1ml
免疫原 KLH conjugated synthetic peptide derived from Rb Anti-phospho-APS(Ser598)
亚型 IgG
产品应用 WB=1:100-500 Elisa=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1/20-1/100
(石蜡切片需做抗原修复)
研究领域 细胞生物 免疫学 神经生物学 信号转导 细胞凋亡 激酶和磷酸酶 内分泌病
产品介绍 APS (adapter protein with Pleckstrin homology and Src homology 2 domains) is a member of the Lnk family, an adaptor protein that is involved in B cell signaling, insulin signaling and cytoskeletal reorganisation. A PH and an SH2 domain containing adaptor protein that links activated tyrosine kinases to signaling pathways. It is tyrosine phosphorylated by JAK2, KIT and other kinases during B cell receptor stimulation of many different cytokines, chemokines and leukokines. APS has been shown to inhibit the JAK STAT pathway in collaboration with cCbl.
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