Recombinant Murine gAcrp30,鼠类的gAcrp30重组

Recombinant Murine gAcrp30

产品编号:

450-27

别名:

apm-1

描述:

gAcrp30 is a naturally occurring globular protein, obtained by proteolytic processing of adiponectin. Adiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein. Like Adiponectin, gAcrp30 is capable of decreasing hyperglycemia and reversing insulin resistance. Additionally, gAcrp30 has been shown to be an important factor in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids （FFAs）. The signaling receptors for adiponectin and gAcrp30 have recently been identified and names AdipoR1 and AdipoR2. AdipoR2 is predominantly expressed in the liver. Recombinant murine gAcrp30 is a 16.6 kDa protein consisting of 145 amino acid residues.

氨基酸序列:

MKGEPGEAAY MYRSAFSVGL ETRVTVPNVP IRFTKIFYNNHYDGSTGK FYCNIPGLYY FSYHITVYMK DVKVSLFKKD KAVLFTYDQY QEKNVDQASG SVLLHLEVGD QVWLQVYGDG DHNGLYADNV NDSTFTGFLL YHDTN

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

Determined by its ability to inhibit the proliferation of murine myeloid cell lines M1. The ED₅₀ for this effect is ≤ 15 µg/ml.