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重组人的骨形态发生蛋白-4BMP-4

时间:2013-06-17      阅读:1435

Synonyms :
BMP-2B, DVR4
Description :
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein.
Catalog #:
120-05
Source :
HeLa cells
Stability :
The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted BMP-4 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles.
Purity :
Greater than 97% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Biological Activity :
Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.
AA Sequence :
HHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP SAISMLY LDEYDKVVLK NYQEMVVEGC GCR
PubMed Link :
BMP-4
Country of Origin :
USA
 

 
 
Size A
1µg
$75 
 
 
Size B
5µg
$185 
 
 
 
 
 

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