SOLARBIO/索莱宝 品牌
生产厂家厂商性质
北京市所在地
| 英文名称 | Anti-NSE Monoclonal Antibody |
|---|---|
| 宿主 | Mouse |
| 别名 | Enolase 2;Neuron specific gamma enolase;ENOG;Eno 2 |
| 应用 | WB |
| 稀释比例 | WB 1:1000-3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 47kDa |
| Gene ID | 2026 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG1 |
| 免疫原 | A synthetic peptide coupled to KLH |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide coupled to KLH |
| Subcellular Locations | Cytoplasm Cell membrane |
| Swiss Prot | P09104 |
| 克隆号 | 1.30E+03 |
| 克隆类型 | Monoclonal Antibody |
| 背景资料 | Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma). The alpha subunit is expressed in most tissues and the beta subunit only in muscle. The gamma subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE (neuron specific enolase) is found in elevated concentrations in plasma in certain neoplasias. These include pediatric neuroblastoma and small cell lung cancer. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms. |
