pVSV-G 载体说明书
时间:2013-08-07 阅读:2706
-
提供商
上海起发实验试剂有限公司 -
资料大小
85523 -
资料图片
点击查看 -
下载次数
352次 -
资料类型
pdf -
浏览次数
2706次
时间:2013-08-07 阅读:2706
提供商
上海起发实验试剂有限公司资料大小
85523资料图片
点击查看下载次数
352次资料类型
pdf浏览次数
2706次型号 | 载体名称 | 出品公司 | 载体用途 |
VMC0386 | pVSV-G | Clontech | 慢病毒包装载体 |
pVSV-G expresses the G glycoprotein of the vesicular stomatitis virus (VSV-G) under the control of the CMV immediate-early promoter. VSV-G is used in pseudotyping of Moloney Murine Leukenia Virus (MMLV)-based retroviral vectors by mediating viral entry. VSV-G interacts with phospholipid components of the target cell membrane and fosters the fusion of viral and cellular membranes. VSV-G does not require a cell surface receptor and can serve as a surrogate viral envelope protein. pVSV-G Vector includes IVS, a synthetic intron known to enhance the stability of the mRNA, the Col E1 origin of replication and bacterial ampicillin rsistance (Ampr) gene for propagation and antibiotic selection in bacteria.