Background: Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death.

Specificity : ·anti-Lamin B Receptor is a rabbit monoclonal antibody unconjugated

·specific for anti-Lamin B Receptor of human, rat, mouse 

·use for western blot, elisa, immunoprecipitation

and immunohistochemistry

·affinity chromatography purification, purity :>95%

·isotype: IgG

·mol wt: 67-71kDa

Application :· Immunohistochemistry: 1:100-500

· ELISA: 1:500-1000

· Western blotting 1:100-500

· Optimal working dilutions must be determined by the end user

上海安研，提供Lamin B Receptor抗体相关抗原

Lamin B Receptor抗原

Lamin B Receptor antigen