T细胞活化抗人CD3单克隆抗体（Functional，clone: OKT3）可以与TCR复合物结合，激活T细胞。SAFIRE(Sodium Azide Free Immensely Reduced Endotoxins) 类产品是BioGems品牌下的功能性抗体产品。

T细胞活化抗人CD3单克隆抗体的克隆号是OKT3。OKT3单克隆抗体特异性结合T细胞的CD3/TCR 复合物（T lymphocyte antigen receptor，T细胞抗原受体）的ε 链。CD3复合物包含γ, δ, and ε三条链，是TCR复合物的一部分，所有成熟T细胞都会表达。CD3可以增强信号转导的抗原识别。

T细胞活化抗人CD3单克隆抗体订购信息

T细胞活化抗人CD3单克隆抗体产品保存和质控

产品原液保存在4°C。不能冷冻。单克隆抗体经过亲和层析纯化。内毒素水平：蛋白质小于0.01 EU/µg，鲎试剂检测法。

T细胞活化抗人CD3单克隆抗体英文版说明

The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.

The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.

Preperation: The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Formulation: Phosphate-buffered aqueous solution, ph7.2.

References: Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Adair, J. R., Athwal, D. S., Bodmer, M. W., Bright, S. M., Collins, A. M., Pulito, V. L., ... & Jolliffe, L. K. (1994). Humanization of the murine anti-human CD3 monoclonal antibody OKT3. Human Antibodies, 5(1), 41-47.

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