cobioer/科佰生物 品牌
代理商厂商性质
南京市所在地
hTACI Effector Reporter Cell
面议EIF1AX p.R62G Reference Standard
面议EIF1AX p.I77S Reference Standard
面议KLB Effector Reporter Cell
面议LTBR Effector Reporter Cell
面议Epstein-Barr Virus (EBV) Reference Standard(Burkit
面议Epstein-Barr Virus (EBV) Reference Standard(Burkit
面议FOXL2 p.C134W Reference Standard
面议SMN1 E7-E8Del (muscle atrophy) Reference Standard
面议HLA-B*27:07 Reference Standard
面议HLA组织配型基因分型标准品III
面议HLA-B*13:01 Reference Standard
面议Panel-Ref® BRCA1/2 Germline Mutation Cocktail II | ||||||||
Cat No. | CBP90018 | |||||||
Description | 主要包含BRCA1和BRCA2的SNV和indel,用于相关的试剂盒和Panel检测服务的质控。 | |||||||
Gene | Clinical significance | Allele origin | mRNA | DNA change | AA change | %AF | Cosmic ID | Chr position (GRCh37) |
BRCA1 | Benign | Germline | NM_007300.4 | c.4900A>G | p.S1634G | 50.00% | COSM3755559 | chr17:41223094 |
BRCA1 | Benign | Germline | NM_007300.4 | c.4308T>C | p.S1436= | 50.00% | COSM4416374 | chr17:41234470 |
BRCA1 | Benign | Germline | NM_007300.4 | c.3548A>G | p.K1183R | 50.00% | COSM148277 | chr17:41244000 |
BRCA1 | Benign | Germline | NM_007300.4 | c.3113A>G | p.E1038G | 50.00% | COSM3755562 | chr17:41244435 |
BRCA1 | Benign | Germline | NM_007300.4 | c.2612C>T | p.P871L | 50.00% | COSM148278 | chr17:41244936 |
BRCA1 | Benign | Germline | NM_007300.4 | c.2311T>C | p.L771= | 50.00% | COSM3755565 | chr17:41245237 |
BRCA1 | Benign | Germline | NM_007300.4 | c.2082C>T | p.S694= | 50.00% | N/A | chr17:41245466 |
BRCA1 | Pathogenic | Germline | NM_007300.4 | c.1961del | p.K654Sfs*47 | 50.00% | COSM219054 | chr17:41245594 |
BRCA2 | Benign | Germline | NM_000059.3 | c.3396A>G | p.K1132= | 50.00% | COSM4415775 | chr13:32911888 |
BRCA2 | Likely_benign | Germline | NM_000059.3 | c.4314C>T | p.V1438= | 50.00% | COSM2071377 | chr13:32912806 |
BRCA2 | Benign | Germline | NM_000059.3 | c.4563A>G | p.L1521= | 100.00% | COSM9180822 | chr13:32913055 |
BRCA2 | Benign | Germline | NM_000059.3 | c.6513G>C | p.V2171= | 100.00% | COSM4147689 | chr13:32915005 |
BRCA2 | Benign | Germline | NM_000059.3 | c.7242A>G | p.S2414= | 50.00% | COSM4415347 | chr13:32929232 |
BRCA2 | Conflicting_interpretations_of_pathogenicity | Germline | NM_000059.3 | c.7397T>C | p.V2466A | 100.00% | COSM7335572 | chr13:32929387 |
定标方法:500x WES、DdPCR(部分位点) | ||||||||
Product Information | ||||||||
Intended Use | Research Use Only | |||||||
Unit Size | 1ug/vial * 1 vial | |||||||
Concentration | Download for COA | |||||||
Purity | Download for COA | |||||||
DNA electrophoresis | Download for COA | |||||||
Storage | 4°C | |||||||
Expiry | 36 months from the date of manufacture |