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PTH2R CHO GPCR细胞 PTH2R CHO GPCR细胞 PTH2R CHO GPCR细胞
I. Background | |
PTH2R (Parathyroid Hormone 2 Receptor) is a Protein Coding gene. Diseases associated with PTH2R include Syndromic Intellectual Disability and Chilblain Lupus. Among its related pathways are GPCR downstream signalling and Class A/1 (Rhodopsin-like receptors). | |
II. Description | |
PTH2R CHO 报告基因药靶模型很好的模拟了体内 PTH2R 的信号转导过程,原理见下图所示。 | |
Figure 1. PTH2R CHO 细胞模型原理图 | |
III. Introduction | |
Expressed gene: | PTH2R |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12K+10%FBS+5 μg/ml Puromycin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
Application(s): | Functional assay for PTH2R receptor |
Transducer: | Gs |
IV. Representative Data | |
Figure 2. HTRF cAMP Assay with PTH2R CHO(C24). |