Plasmocin™ prophylactic

Plasmocin™ prophylactic

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2022-01-28 16:47:50
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供货周期:现货;规格:25 mg (10 x 1 ml);货号:ant-mpp;应用领域:生物产业;主要用途:科研;
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产品属性
供货周期
现货
规格
25 mg (10 x 1 ml)
货号
ant-mpp
应用领域
生物产业
主要用途
科研
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深圳欣博盛生物科技有限公司

深圳欣博盛生物科技有限公司

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产品简介

Plasmocin® is a broad-spectrum mycoplasma and related cell wall-less bacteria removal reagent. It is effective against all common mycoplasma strains, both extracellular and intracellular.

详细介绍

Elimination and prevention of mycoplasma contamination in cell cultures

Cell culture treatment using Plasmocin®
Cell culture treatment using Plasmocin®

InvivoGen also offersINVIVOGEN ALSO OFFERS

• MycoStrip™ — Genomic detection strips

• PlasmoTest™ — Colorimetric cell-based assay

Plasmocin® is a broad-spectrum mycoplasma and related cell wall-less bacteria removal reagent. It is effective against all common mycoplasma strains, both extracellular and intracellular.

For maximum efficiency, Plasmocin® contains a formulation of two antibiotics: the first one blocks protein synthesis, and the second one stops DNA replication. Another component, which is actively transported into mammalian cells, ensures that following treatment, cell cultures do not become re-infected. Thus, Plasmocin® is more effective than other reagents on the market in eradicating mycoplasma and preventing resistant strain generation [1]. Many cell lines infected by mycoplasmas have been successfully treated with Plasmocin® [2], including primary cancer cell lines [3], virus-producing cells [4], and induced pluripotent stem cells [5], without inducing any permanent alterations.
 

This mycoplasma removal reagent is available in two formats:


References:

1. Molla Kazemiha V. et al. 2011. Efficiency of Plasmocin on various mammalian cell lines infected by mollicutes in comparison with commonly used antibiotics in cell cultures: a local experience. Cytotechnology. Dec; 63(6):609-20.
2. Uphoff C. C. et al., 2012. Treatment of mycoplasma contamination in cell cultures with Plasmocin. J Biomed Biotechnol. 2012:267678.
3. Rongvaux A. et al., 2014. Development and function of human innate immune cells in a humanized mouse model. Nat Biotechnol. 32(4):364-72.
4. Baronti C. et al., 2013. Mycoplasma removal: simple curative methods for viral supernatants. J Virol Methods. 187(2):234-7.
5. Deng F. et al. 2012. Generation of induced pluripotent stem cells from human Tenon's capsule fibroblasts. Mol Vis. 18:2871-81.
6. Romorini L. et al, 2013. Effect of antibiotics against Mycoplasma sp. on human embryonic stem cells undifferentiated status, pluripotency, cell viability and growth. PLoS One. 8(7):e70267/


Specifications

Plasmocin® Prophylactic (2.5 mg/ml): to prevent mycoplasma contamination, use at 2.5 - 5 µg/ml on a regular basis.

Plasmocin® Treatment (25 mg/ml): to eliminate mycoplasmas, use at 25 µg/ml for 2 weeks.

Endotoxin level: < 2 EU/mg

Physicochemical characterization: pH and appearance

Cell culture tested: potency validated on bacterial reference strains


Contents

Plasmocin® is provided as a cell culture tested, sterile filtered yellow solution.

This product is available at different concentrations:

Room temperature Plasmocin® Prophylactic and Plasmocin® Treatment are shipped at room temperature

Store Upon receipt, the product can be stored at 4°C for 1 month or at -20°C for long-term storage.


如需购买或咨询该产品技术问题,请联系Invivogen一级代理商-欣博盛生物

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