ZO-1抗原,胞质紧密粘连蛋白1/闭锁小带蛋白1抗原
时间:2024-11-01 阅读:97
Recombinant human ZO-1
ZO1_HUMAN; Tight junction protein ZO-1; TJP1; ZO1; Tight junction protein 1; Zona occludens protein 1; Zonula occludens protein 1; ZO1 tight junction protein;
浓度:1mg/ ml
来源:Recombinant Human
纯度:≥95% SDS-PAGE
表达系统:Escherichia coli
标签:His tag
蛋白长度:Full length protein
内毒素水平:<1.000 Eu/µg
纯化方法:HPLC
应用:SDS-PAGE,Western blot,ELISA
Biological activity,immunology research
保存:-20℃
保质期:1年
The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions.The alpha-containing isoform is found in most epithelial cell junctions. The short isoform is found both in endothelial cells and the highly specialized epithelial junctions of renal glomeruli and Sertoli cells of the seminiferous tubules.
多克隆抗体
产品名称:Rabbit Anti-ZO-1 antibody
Rabbit Anti-ZO-1
别名:ZO1_HUMAN; Tight junction protein ZO-1; TJP1; ZO1; Tight junction protein 1; Zona occludens protein 1; Zonula occludens protein 1; ZO1 tight junction protein;
来源:Rabbit
克隆类型:Polyclonal
浓度:1mg/ml
亚型:IgG
应用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,Flow-Cyt=1μg/Test
反应: Human (predicted: Mouse,Rat,Pig,Sheep,Cow,Chicken,Dog,GuineaPig,Goat)
理论分子量:191kDa
免疫原:KLH conjugated synthetic peptide derived from human ZO-1
保存:-20℃
保质期:1年
单克隆抗体
产品名称:Anti-ZO-1 antibody
Mouse Anti-ZO-1
别名:ZO1_HUMAN; Tight junction protein ZO-1; TJP1; ZO1; Tight junction protein 1; Zona occludens protein 1; Zonula occludens protein 1; ZO1 tight junction protein;
来源:Mouse
克隆类型:Monoclonal
浓度:1mg/ml
亚型:IgG
应用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,Flow-Cyt=1μg/Test
反应: Human
理论分子量:191kDa
免疫原:KLH conjugated synthetic peptide derived from human ZO-1
保存:-20℃
保质期:1年
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms.