VAV1抗原,鸟苷酸转换因子VAV1抗原
时间:2024-12-04 阅读:84
Recombinant human VAV1
Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN .
浓度:1mg/ ml
来源:Recombinant Human
纯度:≥95% SDS-PAGE
表达系统:Escherichia coli
标签:His tag N-Terminus
蛋白长度:Full length protein
内毒素水平:<1.000 Eu/µg
纯化方法:HPLC
应用:SDS-PAGE,Western blot,ELISA
Biological activity,immunology research
保存:-20℃
保质期:1年
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
产品名称:Rabbit Anti-VAV1 antibody
Rabbit Anti-VAV1
别名:Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN .
来源:Rabbit
克隆类型:Polyclonal
浓度:1mg/ml
亚型:IgG
应用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反应:Human (predicted: Mouse,Rat,Pig,Cow,Horse)
理论分子量:98kDa
免疫原:KLH conjugated synthetic peptide derived from human VAV1
保存:-20℃
保质期:1年
单克隆抗体
产品名称:Anti-VAV1 antibody
Mouse Anti-VAV1
别名:Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN .
来源:Mouse
克隆类型:Monoclonal
浓度:1mg/ml
亚型:IgG
应用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反应: Human
理论分子量:98kDa
免疫原:KLH conjugated synthetic peptide derived from human VAV1
保存:-20℃
保质期:1年
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.