大鼠、小鼠自动活动跑轮，提供了一种简单方便的方法来测量大鼠、小鼠在长时间活动中对化学或环境刺激的反应。

可连接到52600数据接口和加装ANYmaze行为学分析软件，实现对昼夜节律或运动功能等方面的研究。

型号：1800（大鼠型）、1850（小鼠型）

产品特点

· 适用于大鼠和小鼠 
· 易于监控：兼容多种何数据采集系统 
· 透明的聚碳酸酯笼子，具有的可见性 
· 全不锈钢车轮结构，便于维护

· 可独立工作，也可连接电脑

· 可选配打印机，具有内部存储和电脑软件

· 易于监测，易于维护，多功能接口可同时连接12只笼子

1850型小鼠自动活动跑轮 

· 11850型小鼠跑轮采用经典的25cm直径，由不锈钢制成，配有低摩擦特氟隆衬套，运作非常平稳；

· 小鼠在2mm直径的杆上自由跑到，杆子间隔7mm； 

· 跑轮装在一个透明的聚碳酸酯笼子里，不锈钢金属盖和含U型颗粒料斗的专用盖锁； 
· 小鼠活动笼尺寸：37(h)x26(w)x35(d)cm；

1800型大鼠自主活动跑轮
· 大鼠跑轮的直径为35cm，杆子直径为2mm，杆子的间距为8.8 mm； 
· 大鼠笼尺寸：48(h)x32(w)x47(d)cm；

转数计数器 
· 大鼠和小鼠活动笼配有磁性开关和LCD计数器，可统计转轮累计转数；

· 根据需要，还可以选择不带计数器的1800-S大鼠自动活动跑轮和1850-S型小鼠自主活动跑轮

· 使用数据线与软件在电脑端进行数据收集；

数据采集 
· 配备多功能接口52600，能够同时连接12活动跑轮； 
· 可选配专业的分析软件ANYmaze进行管理，进行分析和统计；

选择52600多功能数据采集接口时，不需要计数器，这时需要选择的型号是：1800-S型大鼠自动活动跑轮和1850-S型小鼠自主活动跑轮。

大鼠活动示意图：

参考文献：

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7.Miletta, Maria Consolata et al. “AgRP neurons control compulsive exercise and survival in an activity-based anorexia model.” Nature metabolism vol. 2,11 (2020): 1204-1211. doi:10.1038/s42255-020-00300-8

8.Brigger, Daniel et al. “Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age.” Nature metabolism vol. 2,8 (2020): 688-702. doi:10.1038/s42255-020-0228-3

9.van Veen, J Edward et al. “Hypothalamic estrogen receptor alpha establishes a sexually dimorphic regulatory node of energy expenditure.” Nature metabolism vol. 2,4 (2020): 351-363. doi:10.1038/s42255-020-0189-6

10.Brocker, David T et al. “Optimized temporal pattern of brain stimulation designed by computational evolution.” Science translational medicine vol. 9,371 (2017): eaah3532. doi:10.1126/scitranslmed.aah3532

11.Janota, Cátia Silva et al. “Shielding of actin by the endoplasmic reticulum impacts nuclear positioning.” Nature communications vol. 13,1 2763. 19 May. 2022, doi:10.1038/s41467-022-30388-3

12.Bobba, Christopher M et al. “Nanoparticle delivery of microRNA-146a regulates mechanotransduction in lung macrophages and mitigates injury during mechanical ventilation.” Nature communications vol. 12,1 289. 12 Jan. 2021, doi:10.1038/s41467-020-20449-w

13.Mridha, Zakir et al. “Graded recruitment of pupil-linked neuromodulation by parametric stimulation of the vagus nerve.” Nature communications vol. 12,1 1539. 9 Mar. 2021, doi:10.1038/s41467-021-21730-2

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15.Nohara, Kazunari et al. “Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge.” Nature communications vol. 10,1 3923. 28 Aug. 2019, doi:10.1038/s41467-019-11926-y

     

    

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