名称：DOTA-RGDV，DOTA偶联多肽RGDV
Studies using a baboon model showed that RGDV selectively inhibits platelet-dependent thrombus formation in vivo. In a study by Kawahara et al. on the inhibitory effects of adhesion oligopeptides on the invasion of squamous carcinoma cells RGDV was the most effective inhibitor amongst the evaluated peptides.
RGDV 是一种四肽，可将附着的化合物递送至血栓或肿瘤细胞等靶点，它增强了***和抗聚集或抗粘连化合物的功效。 RDGV 结合细胞表面的整合素并防止纤维蛋白原与血小板结合。
RGDV is a tetrapeptide that delivers attached compounds to targets such as thrombus or tumor cells; it enhances efficacy of anticancer and anti-aggregation or anti-adhesion compounds. RDGV binds integrins on the surfaces of cells and prevents binding of fibrinogen to platelets.
中文名称：RGDV
英文名：RGDV
CAS号：93674-99-8
单字母：H2N-RGDV-OH
三字母：H2N-Arg-Gly-Asp-Val-COOH
氨基酸个数：4
分子式：C17H31N7O7
平均分子量：445.47
***分子量：445.23
等电点(PI)：6.34
pH=7.0时的净电荷数：-0.02
平均亲水性：1.5
疏水性值：-1.05
来源：Synthetic
纯度：95%、98%
盐体系：可选TFA、HAc、HCl或其它
生成周期：2-3周
储存条件：-20 ± 5 °C
相关试剂列表：
DOTA-(CONH2)3 913528-04-8
DOTA-(COOt-Bu)3 137076-54-1
DOTA-(COOt-Bu)3-azide 1402795-92-9
DOTA-(COOt-Bu)3-butyne 2125661-54-1
DOTA-(COOt-Bu)3-C2-NH2 173308-19-5
DOTA-(COOt-Bu)3-C4-NH2 1402393-59-2
DOTA-(COOt-Bu)3-Mal 1613382-10-7
DOTA-(COOt-Bu)3-NHFmoc-Lys 479081-06-6
DOTA mono-NHS ester 170908-81-3
DOTA-(COOt-Bu)3-NHS 819869-77-7
供应商：陕西新研博美生物科技有限公司
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