Recombinant human Zyxin
ESP2; HED2; ZYX; Zyxin2.
浓度：1mg/ ml
来源：Recombinant Human
纯度：≥90% SDS-PAGE
表达系统：Mammalian
标签：His tag N-Terminus
蛋白长度：Full length protein
内毒素水平：<1.000 Eu/µg
纯化方法：HPLC
应用：SDS-PAGE，Western blot，ELISA
Biological activity,immunology research
保存：-20℃
保质期：1年
Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.
单克隆抗体
产品名称：Anti-Zyxin antibody
Mouse Anti-Zyxin
别名：ESP2; HED2; ZYX; Zyxin2.
来源：Mouse
克隆类型：Monoclonal
浓度：1mg/ml
亚型：IgG
应用： WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,Flow-Cyt=1:20-1:100,ICC/IF=1:50-1:200,IF=1:50-1:200,IP=1:20-1:50
反应: Human
理论分子量：61kDa
免疫原：KLH conjugated synthetic peptide derived from human Zyxin
保存：-20℃
保质期：1年
多克隆抗体
产品名称：Rabbit Anti-Zyxin antibody
Rabbit Anti-Zyxin
别名：ESP2; HED2; ZYX; Zyxin2.
来源：Rabbit
克隆类型：Polyclonal
浓度：1mg/ml
亚型：IgG
应用： WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,Flow-Cyt=1:20-1:100,ICC/IF=1:50-1:200,IF=1:50-1:200,IP=1:20-1:50
反应: (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)
理论分子量：61kDa
免疫原：KLH conjugated synthetic peptide derived from human Zyxin
保存：-20℃
保质期：1年
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
