Recombinant human WASP protein
Eczema thrombocytopenia; IMD2; SCNX; THC; THC1; Thrombocytopenia 1 (X linked); U42471; Was; WASp; WASP_HUMAN; Wiskott Aldrich syndrome (eczema thrombocytopenia); Wiskott Aldrich syndrome; Wiskott Aldrich syndrome protein; Wiskott-Aldrich syndrome protein.
浓度：1mg/ ml
来源：Recombinant Human
纯度：≥95% SDS-PAGE
表达系统：Escherichia coli
标签：His tag
蛋白长度：Full length protein
内毒素水平：<1.000 Eu/µg
纯化方法：HPLC
应用：SDS-PAGE，Western blot，ELISA
Biological activity,immunology research
保存：-20℃
保质期：1年
The Wiskott-Aldrich syndrome (WAS) is a disorder that results from a monogenic defect that has been mapped to the short arm of the X chromosome. WAS is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative disease. The gene that is mutated in the syndrome encodes a proline-rich protein of unknown function designated WAS protein (WASP). A clue to WASP function came from the observation that T cells from affected males had an irregular cellular morphology and a disarrayed cytoskeleton suggesting the involvement of WASP in cytoskeletal organization. Close examination of the WASP sequence revealed a putative Cdc42/Rac interacting domain, homologous with those found in PAK65 and ACK. Subsequent investigation has shown WASP to be a true downstream effector of Cdc42.
产品名称：Rabbit Anti-WASP protein antibody
Rabbit Anti-WASP protein
别名：Eczema thrombocytopenia; IMD2; SCNX; THC; THC1; Thrombocytopenia 1 (X linked); U42471; Was; WASp; WASP_HUMAN; Wiskott Aldrich syndrome (eczema thrombocytopenia); Wiskott Aldrich syndrome; Wiskott Aldrich syndrome protein; Wiskott-Aldrich syndrome protein.
来源：Rabbit
克隆类型：Polyclonal
浓度：1mg/ml
亚型：IgG
反应：Human,Mouse (predicted: Rat,Rabbit,Cow)
应用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
理论分子量：53kDa
免疫原：KLH conjugated synthetic peptide derived from human WASP protein
保存：-20℃
保质期：1年
产品名称：Anti-WASP protein antibody
Mouse Anti-WASP protein
别名：Eczema thrombocytopenia; IMD2; SCNX; THC; THC1; Thrombocytopenia 1 (X linked); U42471; Was; WASp; WASP_HUMAN; Wiskott Aldrich syndrome (eczema thrombocytopenia); Wiskott Aldrich syndrome; Wiskott Aldrich syndrome protein; Wiskott-Aldrich syndrome protein.
来源：Mouse
克隆类型：Monoclonal
浓度：1mg/ml
亚型：IgG
反应：Human
应用：WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反应: Human
理论分子量：53kDa
免疫原：KLH conjugated synthetic peptide derived from human WASP protein
保存：-20℃
保质期：1年
The Wiskott-Aldrich syndrome (WAS) is a disorder that results from a monogenic defect that has been mapped to the short arm of the X chromosome. WAS is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative disease. The gene that is mutated in the syndrome encodes a proline-rich protein of unknown function designated WAS protein (WASP). A clue to WASP function came from the observation that T cells from affected males had an irregular cellular morphology and a disarrayed cytoskeleton suggesting the involvement of WASP in cytoskeletal organization. Close examination of the WASP sequence revealed a putative Cdc42/Rac interacting domain, homologous with those found in PAK65 and ACK. Subsequent investigation has shown WASP to be a true downstream effector of Cdc42.
