MedChemExpress LLC >> 进入商铺
2025/1/10 16:32:19MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务。
MCE 国际站:Patritumab deruxtecan
品牌:MedChemExpress (MCE)
货号:HY-P99813
CAS:2227102-46-5
Synonyms:HER3-DXd; U3-1402
纯度:0.9908
存储条件:请按照分析证书中建议的条件储存产品。
运输条件:使用干冰运输。
产品活性:Patritumab deruxtecan (HER3-DXd) 是一种抗体-活性分子偶联物 (ADC),由全人抗 HER3 IgG1 单克隆抗体 Patritumab (HY-P99275) 通过基于四肽的可裂解接头连接到拓扑异构酶 I 抑制剂有效载荷组成 [1]。
热销产品:A-674563 | Esculentoside A | Cytarabine triphosphate (trisodium) | Eupalinolide K | FM-red | Methylene Blue | Farnesol | MI-3454 | ML204 | Seclidemstat
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献:
[1]. Koyama K, et al. Patritumab deruxtecan (HER3-DXd), a novel HER3 directed antibody drug conjugate, exhibits in vitro activity against breast cancer cells expressing HER3 mutations with and without HER2 overexpression. PLoS One. 2022 May 3;17(5):e0267027.