Dexamethasone（地塞米松）-化工仪器网-手机版

上海浩然生物技术有限公司

地塞米松

地塞米松，又叫德沙美松、氟甲强的松龙是抗炎、抗过敏药物。主要作为危重疾病的急救用药和各类炎症的治疗。

英文名：dexamethasone

异名：德沙美松;氟甲强的松龙;氟甲去氢氢化可的松;氟美松;甲氟烯索 ,地塞米松，Acidocont, Deronil, Dexacortal, dexametona, Flumeprednisolon等。

化学名：（11β，16α）-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione

CAS号：50-02-2

Sigma相关产品资料：

Sigma D1756Dexamethasone ≥98% （HPLC）, powder

Synonym:	9α-Fluoro-16α-methylprednisolone, Prednisolone F, （11β,16α）-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione
CAS Number:	50-02-2
Linear Formula:	C₂₂H₂₉FO₅
Molecular Weight:	392.46
Beilstein Registry Number:	2066651
EC Number:	200-003-9
MDL number:	MFCD00064136
PubChem Substance ID:	24893536

Description

Frequently Asked Questions	Live Chat and Frequently Asked Questions are available for this Product.
Reconstitution	Dilute 1 mg/ml stock solution 1:50 with sterile media and store frozen in working aliquots to avoid repeated freeze-thaw.
Biochem/physiol Actions	Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

性质

assay	≥98% （HPLC）
form	powder
color	off-white
mp	262-264 °C（lit.）
solubility	ethanol: 1 mg/mL
Gene Information	human ... ABCB1（5243）, CYP3A4（1576）, IL4（3565）, IL5（3567）, NR3C1（2908）
	rat ... Ar（24208）, Nr3c1（24413）, Tnf（24835）
	mouse ... Abcb1a（18671）, Abcb1b（18669）, Ifng（15978）, Nos2（18126）, Ptgs2（19225）, Tnf（21926）
storage temp.	2-8°C

安全性

Personal Protective Equipment	dust mask type N95 （US）, Eyeshields, Faceshields, Gloves
Hazard Codes	Xi
Risk Statements	43
Safety Statements	36/37
WGK Germany	2
RTECS	TU3980000

Dexamethasone（地塞米松）