公司拥有ABGENT、B-bridge、IBL-America、R&D、CST、MBL、SAB、KPL、Santa、Abnova、LifeSpan等谷氧还蛋白2抗体品牌全年代理权，价格行业优势明显。
英文名称 Anti-Glutaredoxin 2
中文名称 谷氧还蛋白2抗体
别 名 bA101E13.1 （GRX2 glutaredoxin （thioltransferase） 2）; bA101E13.1; CGI133; Glrx2; GLRX2_HUMAN; Glutaredoxin-2; Glutaredoxin-2, mitochondrial; GRX2; mitochondrial.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep
产品类型 一抗
研究领域 细胞生物 信号转导 新陈代谢 表观遗传学
46748FSH-R（Follicle-stimulating hormone receptor precursor） 促卵泡刺激素受体抗原 0.5mg
46749FSH（Follicle-stimulating hormone precursor） 促卵泡刺激素抗原 0.5mg
46750GABRA1（gamma-aminobutyric acid （GABA） A receptor, alpha 1） γ1氨基丁酸A型受体α1抗原 0.5mg
46751GABAB1（GABAb Receptor 1） g-氨基丁酸B1受体（多肽） 0.5mg
46752GABABR2/GB2（GABA B Receptor 2） γ1氨基丁酸A型受体B2抗原 0.5mg
46753GAD-67 （glutamate decarboxylase 67） 谷氨酸脱羧酶-67抗原 0.5mg
46754GADD153（Growth arrest and DNA damage-inducible 153） 生长抑制DNA损伤基因153抗原 0.5mg
46755phospho GAP-43（pSer41）（phospho Growth associated protein 43 ） 磷酸化神经生长相关蛋白43抗原 0.5mg
46756GAPDH 3-磷酸甘油醛脱氢酶（人）抗原 0.5mg
46757CXCR3/CD183 peptide 细胞表面趋化因子受体3抗原 0.5mg
46758GATA-3（GATA binding factor 3） GATA结合蛋白3抗原 0.5mg
46759GATA-4（GATA binding factor 4） GATA结合蛋白4抗原 0.5mg
46760Gax（growth arrest-specific homeobox） 生长终止特异性同源盒基因抗原 0.5mg
46761GDF8/MSTN（growth differntiation factor 8） 生长分化因子8抗原 0.5mg
46762GDNF （Glial cell line-derived neurotrphic factor） 胶质细胞源性神经营养因子抗原 0.5mg
46763Gelsolin 凝溶胶蛋白抗原 0.5mg
46764GFP 绿色荧光蛋白 0.5mg
46765GFP 绿色荧光蛋白 0.5mg
46766GITR （glucocorticoidinduced tumor necrosis factor receptor） 糖皮质激素诱导肿瘤坏死因子受体抗原 0.5mg
46767GLI1（GLI-Kruppel family member 1） 下游转录因子Gli1蛋白抗原 0.5mg
46768GLP-1/KG-31（Glucagon-like peptide-1） peptide 胰高血糖素样肽-1（多肽） 0.5mg
46769GLP-1 peptide 胰高血糖素样肽-1（多肽） 0.1mg
46770GLP-1R peptide 胰高血糖素样肽-1受体多肽 0.5mg
46771GLUT3（Glucose transporter 3） 葡萄糖转运蛋白3抗原 0.5mg
46772GM-CSF（Granulocyte-Macrophage Colony Stimulating Factors） 粒细胞-巨噬细胞克隆刺激因子抗原 0.5mg
蛋白分子量 predicted molecular weight: 16kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Glutaredoxin 2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione （GSH）, but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
Function : Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione （GSH）, but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
Subunit : Monomer; active form. Homodimer; inactive form. The homodimer is probably linked by 1 2Fe-2S cluster.
Subcellular Location : Mitochondrion and Nucleus.
Tissue Specificity : Widely expressed. Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta and lung. Not expressed in peripheral blood leukocytes.
Similarity : Belongs to the glutaredoxin family.
Contains 1 glutaredoxin domain.
Database links : UniProtKB/Swiss-Prot: Q9NS18.1