公司拥有ABGENT、B-bridge、IBL-America、R&D、CST、MBL、SAB、KPL、Santa、Abnova、LifeSpan等 葡萄糖苷酶2β/Glucosidase IIβ抗体品牌全年代理权，价格行业优势明显。
英文名称 Anti-Glucosidase 2 subunit beta
中文名称 葡萄糖苷酶2β/Glucosidase IIβ抗体
 葡萄糖苷酶2β/Glucosidase IIβ抗体 别 名 80K-H protein; AGE-binding receptor 2; AGE-R2; G19P1; GLU2B_HUMAN; Glucosidase 2 subunit beta; Glucosidase II beta subunit; Glucosidase II subunit beta; Hepatocystin; PCLD; PKCSH; PLD1; PRKCSH; Protein kinase C substrate 60.1 kDa protein heavy chain; Protein kinase C substrate 80 Kda protein; Protein kinase C substrate 80K-H; Protein kinase C substrate, 80 Kda protein.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse
产品类型 一抗
研究领域 肿瘤 细胞生物 信号转导 激酶和磷酸酶
46801HBA1（hemoglobin alpha 1） 人类血红蛋白α1抗原 0.5mg
46802VWCE/URG11（von Willebrand factor C and EGF domain-containing） 乙型肝炎病毒X蛋白（HBxAg）抗原 0.5mg
46803URGCP/URG4（Up-regulator of cell proliferation） 乙型肝炎病毒X蛋白（HBxAg）抗原 0.5mg
46804URGCP/URG4（Up-regulator of cell proliferation）C terminal 肝炎病毒X蛋白（HBxAg）C端抗原 0.5mg
46805Beta-HCG （Human chorionic gonadotropin Beta） 人beta 亚基人绒毛膜促性腺激素抗原 0.5mg
46806Alpha-HCG（Human chorionic gonadotropin Alpha ） 人α亚基人绒毛膜促性腺激素多肽抗原 0.5mg
46807HCFHrp/BTA（Bladdertumor antigen）human 膀胱肿瘤抗原 0.5mg
46808CD36L1/SRB1 peptide 高密度脂蛋白受体/清道夫受体抗原 0.5mg
46809HER2 receptor（NT）（erbB-2 isoform 2 receptor N-Terminus） c-erbB-2受体抗体（N端） 0.5mg
46810HER2 receptor（NT）（erbB-2 isoform 2 receptor N-Terminus） c-erbB-2受体抗原（N端） 0.5mg
46811HGF（hepatocyte growth factor） 肝细胞生长因子抗原 0.5mg
46812HHV8/ORF50（Human herpesvirus 8 type P） 人类疱疹病毒8抗原 0.5mg
46813HHV8/ORF50（Human herpesvirus 8 type P） 人类疱疹病毒8抗原 0.5mg
46814HHV8/ORF K2（Human herpesvirus 8 type P） 人类疱疹病毒8抗原 0.5mg
46815HIF-1 Beta/ARNT1（Hypoxia-inducible factor-1 Beta） 缺氧诱导因子1β 抗原 0.5mg
46816HIF-2 Alpha （Hypoxia-inducible factor-2 Alpha） 缺氧诱导因子2α 抗原 0.5mg
46817Histone H1b（Histone H1.4） 组蛋白H1b抗原 0.5mg
46818HDAC1/HD1（histone deacetylase 1） 组织蛋白去乙酰化酶1抗原 0.5mg
46819Flag-Tag （CT） Flag Tag标签多肽 1mg
46820DYKDDDDK Tag（CT）/Flag-Tag 标签DYKDDDDK Tag分支肽 0.5mg
46821T7 tag（recombinant T7-tagged proteins） T7 tag标签抗原 0.5mg
46822V5 tag（recombinant V5-tagged protein） V5 tag多肽抗原 0.5mg
46823KT3 tag KT3 tag标签抗原 0.5mg
 葡萄糖苷酶2β/Glucosidase IIβ抗体46824VSV-G tag（vesicular stomatitis virus glycoprotein） VSV-G tag标签抗原 0.5mg
46825HLA-DR（human leukoyte Antigen DR） HLA-DR抗原 0.5mg
蛋白分子量 predicted molecular weight: 58kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Glucosidase 2 subunit beta
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
 葡萄糖苷酶2β/Glucosidase IIβ抗体产品介绍 Trimming of glucoses from N-linked core glycans on newly synthesized glycoproteins occurs sequentially through the action of Glucosidases I and II in the endoplasmic reticulum （ER）. Glucosidase II is an ER-localized enzyme that contains a and b subunits （Glucosidase IIa and Glucosidase IIb） which form a defined heterodimeric complex. Glucosidase IIa is the catalyitc core of the enzyme and can function independently of the b subunit. The sequence of Glucosidase IIb encodes protein rich in glutamic and aspartic acid with a putative ER retention signal （HDEL） at the C-terminus. The phosphorylated form of Glucosidase IIb is localized in the plasma membrane and is highly expressed in FGF-stimulated fibroblasts and epidermal carcinoma cells. Glucosidase IIb was first purified from a human carcinoma cell line as a potential substrate for protein kinase C. Through the HDEL signal at the C-terminus, Glucosidase IIb retains the complete complex in the ER.
Function : Regulatory subunit of glucosidase II.
Subunit : Heterodimer of a catalytic alpha subunit （GANAB） and abeta subunit （PRKCSH）. Binds glycosylated PTPRC （By similarity）.
Subcellular Location : Endoplasmic reticulum.
DISEASE : Defects in PRKCSH are a cause of polycystic liver disease （PCLD） [MIM:174050]. PCLD is an autosomal dominant disorder and is characterized by the presence of multiple liver cysts of biliary epithelial origin. PCLD is a distinct clinical and genetic entity that can occur independently from autosomal dominant polycystic kidney disease （ADPKD） [MIM:173900], which in a considerable but uncertain proportion of cases is associated with hepatic cysts.
Similarity : Contains 2 EF-hand domains.
Contains 1 PRKCSH domain.
Database links : UniProtKB/Swiss-Prot: P14314.2