起订量:
ICP0802/0812 单甲基/双甲基精氨酸抗体HRP标记
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代理商南宁市蓝光生物技术有限公司成立于2008年,坐落在广西南宁市*开发区。是一家由活跃在美国、加拿大生物科技前沿的华人科学家和留学生创建的。其核心技术及研发平台由加拿大ICP免疫公司和美国、加拿大数家拥有*科学家和设备的实验室提供。
蓝光生物的产品和服务包括多肽合成、抗体制备、基因克隆和蛋白表达、免疫学和细胞生物学相关试剂以及技术支持等。目前,公司已开发出近几百种抗体产品,包括:用于蛋白组学和药物筛选的甲基化、乙酰化、磷酸化等翻译后修饰蛋白质组学的抗体和填料;固相非放射性同位素蛋白激酶活性测试盒(PKC,PKA,AKT,SGK和S6K蛋白激酶测试盒)以及用于基础生物医学研究的各种抗体、各种广泛应用于科研的标记第二抗体。这些产品可应用于染色体修饰、细胞周期、细胞周期检验点、细胞凋亡、核因子、神经因子、细胞因子、酪氨酸激酶、翻译调控因子、淋巴细胞信号传导因子、糖代谢等细胞信号传导通路的科学研究。其中,用于药物筛选和基础科研的非放射性同位素蛋白激酶活性测试盒属世界*;自主研发的甲基化、乙酰化、磷酸化特异性抗体及亲和色谱填料等翻译后修饰蛋白质组学抗体和填料等系列产品国内外。客户用我们的产品进行科学研究,论文发表在SCIENCE、NATURE、CELL等高质量的学术杂志上。
“服务科学,创造价值,贴心服务,口碑销售”是南宁蓝光生物一贯发展的宗旨;以顾客为关注焦点,满足顾客的要求是我们永远的追求;*的技术,*的质量,上等的服务和无微不至的售后服务将是我们无悔的选择,衷心希望我们的产品能为您的科研助上一臂之力。
Catalog # ICP0802
Product Description | This antibody was raised from rabbits that were immunized with NG-mono-methyl arginine-KLH conjugates and was specifically isolated and affinity purified using the monomethyl-arginine antigen. The affinity purified methyl arginine antibodies are conjugated to peroxidase (HRP) and are useful for detection, isolation and localization of proteins with NG-methylated arginine residues. |
| Antigen Structure |
Species | Rabbit | ||
Formulation | 250 µg/mL in stabilizing buffer with 50% glycerol | ||
Immunogen | N5-mono-methyl arginine-KLH conjugates | ||
Purification | Antigen-specific affinity chromatography followed by absorption with dimethyl arginine | ||
Conjugation | Reductive amination; HRP/Ab ratio: 2:1 | ||
Specificity | The antibody recognizes proteins with methylated arginine residues. It does not cross react with acetylated proteins or mono- and dimethylated proteins. | ||
Species Tested | Human, mouse and pig | ||
Applications | ELISA (1:2000); WB (1:1000); IP (5 µg/mg protein sample); IF (5 µg/mL) | ||
Scientific Description | Arginine methylation is a very common post-translational modification that occurs predominantly in the nucleus. The main pool of proteins that are modified possess RNA binding properties. More broadly, arginine methylation has been implicated in a variety of cellular processes including protein trafficking, signal transduction and transcriptional regulation. | ||
Storage & Stability | Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly. | ||
Product Specific References | 1. Mol Microbiol. 2007. 65: 590-606. doi:10.1111/j.1365-2958.2007.05831.x |
Catalog # ICP0812
Product Description | This antibody is raised from rabbits that were immunized with NG,NG-dimethyl arginine-KLH conjugates and specifically isolated and affinity purified using the NG,NG-dimethyl arginine antigen. The affinity purified methyl arginine antibody is useful for detection, isolation and localization of proteins with methylated arginine (asymmetric dimethylation) residues. |
|
Antigen Structure |
Species | Rabbit | ||
Formulation | 250 µg/mL in stabilizing buffer with 50% glycerol | ||
Immunogen | N5,NG-dimethyl arginine-KLH conjugates | ||
Conjugation | Aldehyde-activated HRP via reductive amination HRP/Ab ratio: 3:1 | ||
Specificity | The antibody recognizes proteins with dimethylated arginine residues. It does not cross react with acetylated proteins or mono-methylated proteins. | ||
Species Tested | Human, mouse and pig | ||
Applications | ELISA (1:2000); WB (1:1000); IP (5 µg/mg protein sample); IF (5 µg/mL); IHC (5 µg/mL) | ||
Scientific Description | Arginine methylation is a very common post-translational modification that occurs predominantly in the nucleus. The main pool of proteins that are modified in such a way possess RNA binding properties. More broadly, arginine methylation has been implicated in a variety of cellular processes including protein trafficking, signal transduction and transcriptional regulation. | ||
Storage & Stability | Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is three years from date of shipping if stored properly. | ||
Product Specific References | 1. Mol Microbiol. 2007. 65: 590-606. doi:10.1111/j.1365-2958.2007.05831.x |