RF9

产品活性：RF9 是一种有效且有选择性的神经肽FF受体 (Neuropeptide FF receptor) 拮抗剂 ，对于 hNPFF1R 和 hNPFF2R 的 K_i 值分别为 58±5 和 75±9 nM。

研究领域：GPCR/G Protein

作用靶点：Neuropeptide Y Receptor

In Vivo: RF9 (10 μg) infused alone does not result in a significant alteration of MAP or heart rate. Conversely, MAP and heart rate increases evoked by NPFF are significantly blocked when NPFF is applied in conjunction with RF9. It is worthy to note that RF9 (30 nmol) significantly reduces the hypothermia induced by morphine (5 nmol).

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