abs126104 Rabbit anti-IL-1β Polyclonal Antibody
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概述 | |
别名 | IL-1 β抗体;Catabolin; H1; IL-1β; Hematopoietin 1; IFN beta inducing factor; IL 1; IL 1 beta; IL 1B; IL1B; IL1F2; Interleukin 1 beta; Interleukin 1 beta precursor; LAF; OAF; Osteoclast activating factor; Preinterleukin beta; Pro interleukin 1 beta; IL1B_HUMAN; Interleukin-1 beta; IL-1 beta |
宿主 | Rabbit |
特异性 | IL-1 Beta |
反应种属 | Human, Mouse, Rat |
预测反应种属 | Dog, Horse, Rabbit |
应用 | FCM: 2ug/T |
分子量 | Predicted molecular weight: 17kD/32kDa |
免疫原 | KLH conjugated synthetic peptide derived from human IL-1 Beta:161-269/269 |
性能 | |
浓度 | 1mg/ml |
纯化方法 | affinity purified by Protein A |
类型 | Polyclonal Antibody |
同种型 | IgG |
储存/保存方法 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
存储溶液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
标记 | Unlabeled |
修饰 | Unmodified |
研究领域 | 细胞生物 免疫学 生长因子和激素 糖蛋白 |
靶标 | |
背景说明 | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]. |
细胞定位 | 分泌型蛋白 |
UniProt | P01584 |