SOLARBIO/索莱宝 品牌
生产厂家厂商性质
北京市所在地
羊抗小鼠IgG-HRP
面议Anti-Lamin B2 Monoclonal Antibody
面议Anti-p90RSK Monoclonal Antibody
面议Anti-Hsp27 Monoclonal Antibody
面议Anti-CBR1 Monoclonal Antibody
面议Anti-ATIC Monoclonal Antibody
面议Anti-hnRNP U Monoclonal Antibody
面议Anti-KAP1/TIF1β Monoclonal Antibody
面议Anti-α-Tubulin Polyclonal Antibody
面议羊抗大鼠IgG-HRP 二抗
面议羊抗兔IgG-HRP solarbio
面议羊抗猪IgG-HRP solarbio
面议Anti-EGFR Monoclonal Antibody
英文名称 | Anti-EGFR Monoclonal Antibody |
---|---|
宿主 | Mouse |
别名 | Epidermal growth factor receptor;erbb 1;Receptor tyrosine protein kinase ErbB 1 |
应用 | WB IP IF |
稀释比例 | WB 1:1000-3000. IP 1:100-300. IF 1:100-200. |
交叉反应 | Human |
蛋白分子量 | 170kDa |
Gene ID | 1956 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG1 |
免疫原 | A synthetic peptide coupled to KLH |
性状 | 液体 |
Public Immunogen Range | A synthetic peptide coupled to KLH |
Subcellular Locations | Secreted Cell membrane |
Swiss Prot | P00533 |
克隆号 | M6 |
克隆类型 | Monoclonal Antibody |
背景资料 | The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. |