药代动力学实验装置系统，flexcell str4000，

美国Flexcell公司，专注于细胞力学培养产品的设计和制造30多年。其体外细胞拉应力、压应力和流体剪切应力加载刺激系统以及配套的培养板、硅胶膜载片等耗材*。其产品成熟度高、成功应用文献量达4000多篇，国内有100多家单位使用，无技术风险和使用风险，已成为细胞力学体外加载模型的黄金标准，是细胞组织力学研究者的shou选

为细胞提供各种形式的流体切应力：稳流式切应力，脉冲式切应力或者往返式切应力。

在经过特殊基质蛋白包被的25mm x 75mm x 1.0mm 细胞培养载片上培养细胞。

计算机控制的蠕动泵可以调节切应力的大小，从0-35 dynes/cm².

通过Osci-Flow液体控制仪提供往返式或者脉冲式的流体切应力。

检测细胞在液流作用下的排列反应。

设备易拆卸并可高温消毒。

可以在经过特殊包被的6个细胞培养载片上同时培养细胞。

可以在提供流体切应力的同时抻拉细胞，测试血管和结绨组织细胞对液体流动的实时反应。

为培育在StageFlexer硅胶模表面或者基质蛋白包被的细胞培养片上的细胞提供切应力。
使用FX-5000T应力加载系统抻拉细胞，并且可以在实验前，实验中或者实验后提供切应力。
计算机控制蠕动泵，调节切应力大小，从0-35 dynes/cm². 
使用标准正立式显微镜实时观察细胞在切应力下的反应。
检测细胞在流体作用下的排列反应。
检测在液体切应力下各种激活剂/抑制剂对细胞反应的影响。
使用荧光团例如FURA-2检测细胞内[Ca2+]ic或者其它离子对切应力的反应。

典型应用文献：

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