Melatonin 是一种激素，可激活褪黑激素受体,在睡眠中起作用。Melatonin 还是一种新型的选择性 ATF-6 抑制剂。(Melatonin is a hormone that activates melatonin receptors and plays a role in sleep. Melatonin is also a novel and selective ATF-6 inhibitor.)
[1]. Kilic U, et al. Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice. Redox Biol. 2017 Apr 5;12:657-665 [2]. Hu C, et al. Neuroprotective effect of melatonin on soluble Aβ1-42-induced cortical neurodegeneration via Reelin-Dab1 signaling pathway. Neurol Res. 2017 Apr 7:1-1 [3]. Rahim I, et al. Melatonin administration to wild-type mice and non-treated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis. J Pineal Res. 2017 Mar 31
