cobioer/科佰生物 品牌
代理商厂商性质
南京市所在地
| CBP73337 | |
| I. Introduction | |
Cell Line Name： | KRAS G12C-Y96C/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
| II.Background | |
KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118). | |
| III. Representative Data | |
1.WB of KRAS G12C-Y96C/BaF3 | |
2.Sanger of KRAS G12C-Y96C/BaF3
Figure 1. KRAS G12C-Y96C/BaF3 G12C
Figure 2. KRAS G12C-Y96C/BaF3 Y96C | |
3.Anti-proliferation assay
Figure 3. CTG Proliferation Assay of BaF3 KRAS G12C/Y96C Cells (C3). | |
