cobioer/科佰生物 品牌
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南京市所在地
CYP2D6*10 Reference Standard
面议CYP2D6*10 Reference Standard
面议GJB2 p.M34T Reference Standard
面议GJB2 p.G4D Reference Standard
面议GJB2 p.G12Vfs*2/p.M34T double mutation Reference S
面议GJB2 p.G12Vfs*2 Reference Standard
面议AI-Edigene® FGFR2(E17)- BICC1(E3) Translocati
面议GJB2 p.E120del/p.M195I double mutation Reference S
面议GJB2 p.L79Cfs*3/p.G59Afs*18 double mutation Refere
面议ERBB2 Amplification Reference Standard (Pair-P6)
面议ERBB2 Amplification Reference Standard (Pair-P2)
面议Package-Ref™ MRD Cocktail Reference Standard
面议 CBP10538 | |
Format | Genomic DNA |
Description | NPM1, nucleophosmin, is a phosphoprotein that shuttles between the nucleus and cytoplasm, and is involved in several cellular processes including ribosomal processing and export, chromatin remodeling, DNA replication and repair, and cell cycle control (PMID: 29157973, PMID: 23436734). NPM1 is frequently mutated in acute myeloid leukemia (PMID: 29157973, PMID: 23436734, PMID: 30122998, PMID: 29785446, PMID: 32203582, PMID: 32609823) and overexpression is implicated with poor prognosis in hematological and solid tumors (PMID: 32071709). |
Technical Data | |
DNA Change | c.829C>T |
AA Change | p.R277W |
Mutation type | Missense_Mutation |
Zygosity | Heterozygous |
Allelic Frequency | 3.58% |
Transcript | NM_002520.7 |
Cosmic ID | COSM3339473 |
Chr position(GRCh37) | chr5:170834761 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | Download for COA |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |