NPM1 p.R277W Reference Standard 标准品

CBP10538NPM1 p.R277W Reference Standard 标准品

参考价: 面议

具体成交价以合同协议为准
2023-04-11 15:37:02
309
属性:
供货周期:现货;规格:1ug;货号:CBP10538;应用领域:生物产业;
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产品属性
供货周期
现货
规格
1ug
货号
CBP10538
应用领域
生物产业
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南京科佰生物科技有限公司

南京科佰生物科技有限公司

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产品简介

NPM1 p.R277W Reference Standard

详细介绍


CBP10538
FormatGenomic DNA
DescriptionNPM1, nucleophosmin, is a phosphoprotein that shuttles between the nucleus and cytoplasm, and is involved in several cellular processes including ribosomal processing and export, chromatin remodeling, DNA replication and repair, and cell cycle control (PMID: 29157973, PMID: 23436734). NPM1 is frequently mutated in acute myeloid leukemia (PMID: 29157973, PMID: 23436734, PMID: 30122998, PMID: 29785446, PMID: 32203582, PMID: 32609823) and overexpression is implicated with poor prognosis in hematological and solid tumors (PMID: 32071709).
  
Technical Data 
DNA Changec.829C>T
AA Changep.R277W
Mutation typeMissense_Mutation
ZygosityHeterozygous
Allelic Frequency3.58%
TranscriptNM_002520.7
Cosmic IDCOSM3339473
Chr position(GRCh37)chr5:170834761
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencingDownload for COA
Storage4℃
Expiry36 months from the date of manufacture


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