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¥1989概述 | |
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描述 | AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor, inhibits human GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respectively, shows >14-fold selectivity against CDK2, CDK5, CDK1 and Erk2. |
别名 | AZD 1080,AZD-1080 |
性能 | |
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保存方法 | store at -20℃ for one year(Powder); in DMSO or others solvent store at 2-4℃ for two weeks, at -80℃ for six months. |
纯度 | >98% |
分子量 | 334.37 |
化学式 | C19H18N4O2 |
分子结构式 | |
溶解性 | DMSO 52 mg/mL (155.51 mM) Water <1 mg/mL Ethanol <1 mg/mL 体内 30% PEG400+0.5% Tween80+5% Propylene glycol 20 mg/mL * <1 mg/ml 指产品微溶或不溶 * 溶解度仅供参考。 |
CAS号 | 612487-72-6 |
外观 | Powder |