Phospho-DARPP-32 （Thr34） Antibody（100ug）

abs131113aPhospho-DARPP-32 （Thr34） Antibody（100ug）

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2024-07-07 17:09:25
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供货周期:一周；
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爱必信（上海）生物科技有限公司

爱必信（上海）生物科技有限公司

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详细介绍

概述
描述DARPP-32 a member of the protein phosphatase inhibitor 1 family. A dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Both dopaminergic and glutamatergic (NMDA) receptor stimulation regulate the extent of DARPP32 phosphorylation, but in opposite directions.
别名DARPP 32; DARPP-32; Dopamine and cAMP regulated neuronal phosphoprotein 32; Dopamine and cAMP regulated neuronal phosphoprotein; Dopamine and cAMP regulated phosphoprotein; Dopamine and cAMP regulated phosphoprotein DARPP 32; Dopamine and cAMP regulated phosphoprotein DARPP32; Dopamine- and cAMP-regulated neuronal phosphoprotein; FLJ20940; IPPD; Neuronal phosphoprotein DARPP 32; PPP1R1B; PPR1B_HUMAN; Protein phosphatase 1 regulatory (inhibitor) subunit 1B; Protein phosphatase 1 regulatory inhibitor subunit 1B; Protein phosphatase 1 regulatory subunit 1B;
克隆类别Polyclonal
反应种属 

Human, Mouse, Rat
来源宿主Rabbit
应用

WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
特异性Phospho-DARPP-32 (Thr34) Antibody detects endogenous levels of DARPP-32 only when phosphorylated at Threonine 34
性能
保存方法Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
浓度1mg/ml
分子量32kDa
功能Inhibitor of protein-phosphatase 1.
纯化方法Immunogen affinity purified
亚细胞定位Cytoplasm,
序列MDPKDRKKIQFSVPAPPSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPEEEASPHQRASGE GHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELGYPREE DEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQGLEGPWERPPPLDESERDGGSED QVEDPALSEPGEEPQRPSPSEPGT

实验结果图

Western blot analysis of DARPP-32 phosphorylation expression in PMA treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Western blot analysis of DARPP-32 phosphorylation expression in PMA treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

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