Source:Goat

Quantity/unitsize:300µg

Description:GoatpolyclonalantibodytoTNFalpha.TNF-alphaisproducedbyavarietyofimmunecellsincludingNKcells,Bcells,Tcellsandmacrophages.Itismultifunctionalproinflammatorycytokinethatbelongstothetumournecrosisfactor(TNF)superfamily.Itcanbindto,andthusfunctionsthroughitsreceptorsTNFRSF1A/TNFR1andTNFRSF1B/TNFBR.Itisinvolvedintheregulationofseveralprocessesincludinglipidmetabolismcelldifferentiationandproliferation,coagulationandapoptosis.Ithasbeenimplicatedinavarietyofdiseases,includingcancerandautoimmunediseases. Alternativenames:APC1,cachectin;tumornecrosisfactorligandsuperfamilymember2,macrophage-derivedTNF,TNF-a,TNFmonocyte-derived,tumornecrosisfactor-alphaantibody.

Form:Polyclonalantibodysuppliedasa100µl(3mg/ml)aliquotinPBS,20%glyceroland0.05%sodiumazide.Thisantibodyisepitope-affinitypurifiedfromgoatantiserum.

Immunogen:PurifiedrecombinanthumanTNF-alphaproducedinE.coli.

Specificity:Detectsabandofapproximately17kDausingRaw264.7celllinebyWesternblot.

Reactivity:Reactsagainsthuman,rat,mouse,canineandmonkeyproteins.

Usage:Westernblot            1:500-1:2,000Immunofluorescence                 NDImmunohistochemistry(paraffin)               NDImmunohistochemistry(frozen)                ND

Reactivitychart Sicgen Antibodies多克隆抗体 300 µg

Storage:Storeat-20Cforlong-termstorage.Storeat2-8Cforuptoonemonth.

Specialinstructions:Avoidfreeze/thawcycles.