品牌
代理商厂商性质
所在地
AMPure XP DNA核酸纯化磁珠A63881
面议Valley biomedical/BioIVT人AB血清Human AB Serum
面议Clodrosome巨噬细胞清除剂clodronateliposomes脂质体
面议脂质体巨噬细胞清除套装(阴离子)Clophosome®-A and Control Liposomes (anionic)
面议自诱导LB培养基Auto Induction Medium
面议CellCover
面议Hibernate® A
面议Biotin-Ahx-Ub-VME
面议Virogen抗Anti-Glutathione antibody抗体
面议正常人AB血清Human AB Serum Heat Inactivated
面议Terrace Biotech抗人肺泡Ⅰ型细胞HT1-56小鼠IgG1单克隆抗体
面议Terrace Biotech抗人肺泡II型细胞HT2-280小鼠IgM单克隆抗体
面议Antigen: Antibodies for Mouse Platelet Depletion
Description: This antibody preparation contains a mixture of purified rat monoclonal antibodies directed against mouse GPIb alpha (CD42b). Targeting of this receptor with divalent IgGs results in profound and irreversible Fc-independent platelet depletion in mice.
Clone: polyclonal anti-GPIb alpha
Isotype: Rat IgG
Form: purif.
Applications: platelet depletion
Size: 0.5 mg
德国Emfret公司专注心血管和血液系统研究用抗体研发和生产,供应的抗体包括清除血液中血小板、流式细胞术鉴定分析小鼠血小板表面糖蛋白,Emfret公司的抗体不仅适用于流失分析、WB检测,还可用于免疫组化/免疫荧光及免疫共沉淀检测。靶向小鼠血小板清除的抗体,是混合物,包含抗小鼠 GPIbα (CD42b) 的纯化大鼠单克隆抗体。 用二价 IgG 靶向该受体会导致小鼠中严重且不可逆的 Fc 非依赖性血小板清除。 血小板清除经常应用于研究血小板的(病理)生理学中的全面作用。
Depletion of mouse platelets by anti-GPIba(R300) treatment
Wild type mice received 2 or 4 µg/g platelet depletion antibodies in 200 µl sterile PBS intravenously and platelet counts were determined at the indicated time points. Results are mean±s.d. of 6 mice per group.
Specificity: This antibody preparation contains a mixture of purified rat monoclonal antibodies directed against mouse GPIb(CD42b). Targeting of this receptor with divalent IgGs results in profound and irreversible Fc-independent platelet depletion in mice1,2. Platelet depletion is frequently used to study the general role of platelets in (patho-) physiology3.
Preparation and Storage: The antibodies were purified from hybridoma cell culture supernatant by Protein G-Sepharose chromatography and contain < 0.00025 ng/μg (< 0.0025 EU/μg) protein endotoxin. Stable for six months from date of shipment when stored at 4°C. KEEP STERILE, the preparation contains no preservative. Aliquots can be stored at -20°C for at least one year. Avoid repeated freezing and thawing.
Usage: This preparation is optimized to reduce the platelet count by >95% within 60 minutes after intravenous injection of 2 μg/g bodyweight. It is recommended to inject the antibodies in a volume of 100-200 μl (diluted with sterile PBS).