关于荧光染料AF594标记刀豆蛋白A，羧基端结合蛋白1(CTBP1)重组蛋白简介-技术文章-西安昊然生物科技有限公司手机版

关于荧光染料AF594标记刀豆蛋白A，羧基端结合蛋白1(CTBP1)重组蛋白简介

时间：2023-09-26 阅读：184

关于荧光染料AF594标记刀豆蛋白A，羧基端结合蛋白1(CTBP1)重组蛋白简介

Objective: To investigate the protective effect of resveratrol on liver injury caused by concanavalin A (Con A). Method: Con A was used to induce liver injury in mice, and resveratrol was administered orally for treatment. After 3 days, blood was collected to detect serum ALT, AST activity, and nitric oxide (NO) content. The activity of liver tissue superoxide dismutase (SOD) and malondialdehyde (MDA) were measured, and pathological changes in liver tissue were observed. The results showed that the activity of ALT and AST in the middle dose group of resveratrol was significantly lower than that in the model group (P<0.01), However, compared with the biphenyl diester group, there was no significant difference (P>0.05); Compared with the model group, the moderate dose group showed a significant increase in SOD activity and a significant decrease in MDA content in liver tissue, with a significant difference (P<0.05); The serum NO content in the high, medium, and low dose groups of resveratrol was significantly lower than that in the model group (P<0.05); The pathological changes of liver tissue in the medium dose group of resveratrol were significantly reduced. Conclusion: Resveratrol has a good protective effect on Con A induced liver injury in mice, and its liver protection mechanism is closely related to the anti lipid peroxidation damage and inhibition of NO production。

产品名称：AF594标记刀豆蛋白A

中文名称：AF594标记刀豆蛋白A

英文名称：AF594 labeled concanavalin A

分类：蛋白标记

溶解性：/

规格：mg

纯度：95%+

储存：/

用途：科研

品牌：昊然生物

刀豆蛋白A（Ricin A Chain）是一种毒性蛋白质，它是由毒刀豆（Ricinus communis）植物产生的一种毒素的组成部分。刀豆蛋白A通常与刀豆蛋白B（Ricin B Chain）一起组成完整的毒素分子，被称为刀豆毒素（ricin）。

刀豆毒素是一种强有毒的蛋白质，它的毒性主要来自于刀豆蛋白A部分。刀豆蛋白B部分具有与细胞膜糖蛋白相互作用的特性，有助于刀豆毒素进入目标细胞。一旦刀豆毒素进入细胞，刀豆蛋白A部分会抑制细胞内的蛋白质合成，从而导致细胞死亡。