FXR Agonist Assay Kit (TR-FRET)

78131FXR Agonist Assay Kit (TR-FRET)

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2023-12-16 14:36:10
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BPS Bioscience Inc.

BPS Bioscience Inc.

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Description

The FXR (Farnesoid X Receptor) Agonist Assay Kit (TR-FRET) is designed to measure binding of the FXR and SRC-1 (Steroid Receptor Coactivator 1) for screening FXR agonists using TR-FRET technology. With this homogeneous kit, the FXR agonist assay can be performed by adding all materials, including the detection reagents, to the wells and incubating the plate for 2-hours at room temperature followed by reading the TR-FRET signal.

Assay Principle

Assay Principle

Upon binding of the agonist to the FXR, SRC-1-Biotin and FXR form a heterodimer, resulting in energy transfer from Tb donor to the dye labeled acceptor.

Synonyms
Nuclear Receptor Subfamily 1 Group H Member 4 kit, Bile Acid Receptor Assay, RIP14 assay kit, HRR1 assay kit
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