KRAS (G12C), Isoform A, BODIPY-GDP Loaded, His-Tag

100537KRAS (G12C), Isoform A, BODIPY-GDP Loaded, His-Tag

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2023-12-17 07:14:50
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BPS Bioscience Inc.

BPS Bioscience Inc.

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●Purchase●DescriptionRecombinanthumanKRAS(GTPase),isoforma,encompassingaminoacids2-186(end)

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Description

Recombinant human KRAS (GTPase), isoform a, encompassing amino acids 2-186 (end). In this construct the N-terminal end of the protein contains a His-tag (6xHis) followed by an optimal TEV protease target sequence that allows cleavage of the His-tag from the protein (TEV: tobacco etch virus cysteine protease, BPS Bioscience #50308). The protein also contains cancer-associated mutation G12C. KRAS (G12C) His-Tag (BPS Bioscience #100413) was affinity purified and was loaded with BODIPY-GDP. Unbound BODIPY-GDP was removed by spin column and the protein is ready for a GDP/GTP exchange assay.

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Synonyms
C-K-RAS, CFC2, K-ras, kRas(G12C), kRas, KRAS proto-oncogene, GTPase, Kirsten Rat Sarcoma virus, NS, NS3, OES, RALD, KRAS1, KRAS2, RASK2, KI-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, c-Ki-ras, c-Ki-ras2
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