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Exalpha 凋亡增殖、炎症、免疫学传染病学和细胞间结构研究-相关技术文章

时间:2024-07-18      阅读:116

Exalpha 凋亡增殖、炎症、免疫学传染病学和细胞间结构研究

 

Exalpha公司简介

Exalpha有限公司于2000年在马萨诸塞州雪莉(美国)成立。该公司主要通过开发和生产抗体来支持生命科学领域的研究人员和科学家。

Exalpha公司产品领域

Exalpha公司其领域涉及信号通路、凋亡、增殖、炎症、免疫学、传染病学和细胞间结构研究等方面。Exalpha主要产品线包括Proliferation&apoptosis, Enzymes&Proteins, Clinical IHC Markers , GPCRs等多个产品线,可提供给全球的科研实验室,制药企业,生物技术和诊断公司,医院等,目前旗下的代理公司遍布全球。

细胞增殖是生物体的重要生命特征,是生物体生长、发育、繁殖以及遗传的基础。监测细胞群的生长对细胞的状态研究很有必要。科研工作者们经常需要检测细胞增殖情况,比如验证抗肿瘤药物的药效时,监测细胞增殖及存活情况;研究肿瘤侵袭与转移模型时,分析细胞转移或侵袭的路径;分析创伤的修复或组织的重建时,检测细胞生长情况等等。检测细胞增殖及活性变化则可以很好的反映细胞的生长状况。

细胞增殖的研究方法

细胞增殖的研究方法有很多种,根据检测原理不同,主要分为DNA合成检测法、代谢活性检测法、细胞增殖标志物检测法等。本文重点介绍DNA合成检测之Brdu检测法,传统DNA合成检测方法使用胸腺嘧啶核苷(3H-TdR)掺入DNA,然后通过放射自显影或闪烁计数对DNA进行定量,该方法由于存在放射性物质、实验周期长、操作繁琐,且需要昂贵的设备,目前已被BrdU5-Bromo-2-deoxyuridine5-溴脱氧尿嘧啶核苷)检测方法取代,BrdU作为一种胸苷类似物,可选择性地掺入增殖细胞的DNA中,而且可稳定存在,并带到子代细胞中,细胞经过固定和变性处理后,可用免疫学方法检测DNABrdU的含量,从而判断细胞的增殖能力。

Exalpha Biologicals品牌BrdU检测试剂盒

因组织细胞内无内源性BrdU存在,可利用BrdU相关抗体来检测和定位掺入活跃增殖细胞新合成DNABrdUExalpha Biologicals 品牌BrdU检测试剂盒的优势在于使用细胞层作为固相,将BrdU试剂掺入微孔板中的细胞,除了对细胞增殖情况进行评估外,还可以从单个培养物中分析细胞数量、形态和细胞抗原等信息。同时Exalpha Biologicals 品牌BrdU检测试剂盒可通过试剂盒自带的固定/变性溶液一步完成细胞固定、透化和DNA变性等实验流程,大大缩短了实验时间。Exalpha Biologicals 品牌BrdU检测试剂盒中包含检测细胞增殖活性所需的所有组分、操作简便、无放射性、广泛的样本适用性,已得到众多科研工作者的青睐。

 

Exalpha公司热销产品

产品名称

货号

规格

BrdU Cell Proliferation Assay Kit

X1327K1

200Tests

chx 10 (Visual system homeobox 2) (NT) Polyclonal Antibody

X1180P

250ug

EBNA 3C Polyclonal Antibody

F125P

250ug

SURF1 Polyclonal Antibody

X1562P

100ug

Bnip3L (IN) (nix) (bcl 2 family) Polyclonal Antibody

X1120P

100ug

chx 10 (Visual system homeobox 2) (CT) Polyclonal Antibody

X1179P

250ug

Microphthalmia Transcription Factor (MiTF) Monoclonal Antibody

X1405M

100ug

EBNA 3A Polyclonal Antibody

F115P

250ug

CD5 PE Single-Color Reagent

0054

100Tests

PTP mu Monoclonal Antibody

P100M

100ug

CD117 FITC Single-Color Reagent

1172

100Tests

Kv1.5 Potassium Channel Polyclonal Antibody

X1501P

100ug

N-SMase Activation Associated Factor Antigen Immunoaffinity Purified   Polyclonal

X2354P

100ug

Chicken anti Glutathione S Transferase (GST), conjugated with HRP

AGST-HRP

0.1 mg

CD7 PE Single-Color Reagent

0074

100Tests

Protein Phosphatase 1 alpha Polyclonal Antibody

P105P

100ug

CD2 PE Single-Color Reagent

0024

100Tests

Kv1.6Potassium Channel Polyclonal Antibody

X1502P

100ug

Degenerative Spermatocyte Homolog 2 (DEGS2) Antigen Immunoaffinity   Purified Polyclonal

X2356P

100ug

CD8 PE Single-Color Reagent

0084

100Tests

Protein Phosphatase 1 beta Polyclonal Antibody

P110P

100ug

CD2 FITC - CD7 PE Bi-Test Reagents (FITC/RPE)

0027S

50Tests

Kv2.1Potassium Channel Polyclonal Antibody

X1503p

100ug

Sphingomyelin Phosphodiesterase 3 Antigen Immunoaffinity Purified   Polyclonal

X2359P

100ug

Chicken anti HA (Hemagglutinin) Epitope

AHA

0.1 mg

CD13 PE Single-Color Reagent

0134

100Tests

Protein Phosphatase 1 beta Polyclonal Antibody

P115P

100ug

CD3 PE Single-Color Reagent

0034

100Tests

Potassium Channel (Kv3.1b ) Polyclonal Antibody

X1504P

100ug

Monocarboxylate Transporter 3 (MCT3) Antigen Immunoaffinity Purified   Polyclonal

X2361P

100ug

Protein Phosphatase 1 gamma 1 Polyclonal Antibody

P120P

100ug

CD61 PE Single-Color Reagent

0614

100Tests

Potassium Channel (Kv4.2 ) Polyclonal Antibody

X1505P

100ug

Zinc Finger Protein GLI1 Antigen Immunoaffinity Purified Polyclonal

X2363P

100ug

Chicken anti HA (Hemagglutinin) Epitope, conjugated with FITC

AHA-F

0.1 mg

CD16 PE Single-Color Reagent

0164

100Tests

Protein Phosphatase 1 gamma 1 Polyclonal Antibody

P125P

100ug

BrdU (bromodeoxyuridine) Monoclonal Antibody

X1028

100ug

Calcium Channel (a1B) Polyclonal Antibody

X1507P

100ug

Monocarboxylate Transport 2 Antigen Immunoaffinity Purified Polyclonal

X2368P

100ug

Chicken anti HA (Hemagglutinin) Epitope, conjugated with HRP

AHA-HRP

0.1 mg

CD18 PE Single-Color Reagent

0184

100Tests

Protein Phosphatase 1 gamma 2 Polyclonal Antibody

P130P

100ug

Muc1 Monoclonal Antibody

X2783M

100ug

Voltage-dependent T-type calcium channel subunit alpha-1E Polyclonal   Antibody

X1509P

100ug

G-Protein Coupled Receptor 94 Antigen Immunoaffinity Purified   Polyclonal

X2373P

100ug

CD19 PE Single-Color Reagent

0194

100Tests

Protein Phosphatase 2 A/A Polyclonal Antibody

P140P

100ug

CD95 Monoclonal Antibody

X2785M

100ug

Calcium Channel (a1G) Polyclonal Antibody

X1510P

100ug

 


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