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2024/3/22 11:24:46MCE 国际站:Val-Cit-PAB-MMAE
CAS:644981-35-1
品牌:MedChemExpress (MCE)
存储条件:4°C, stored under nitrogen
生物活性: Val-Cit-PAB-MMAE 是一种?ADC 的药物-接头偶联物。 Val-Cit-PAB-MMAE 包含 ADC 接头(肽 Val-Cit-PAB)和强效微管蛋白抑制剂 MMAE (HY-15162)。 MMAE 是一种有效的有丝分裂抑制剂,通过抑制微管蛋白聚合[1]。
热销产品:Ribavirin | Belinostat | DBCO-amine | SAICAR | Ulixertinib | KU-55933 | Adenosine 5'-diphosphate | DBCO-(PEG)3-VC-PAB-MMAE | Carfilzomib | Alectinib
研究领域:Antibody-drug Conjugate/ADC Related
作用靶点:Drug-Linker Conjugates for ADC
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献:
[1]. Okeley, et al. Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate. Clinical Cancer Research (2010), 16(3), 888-897.