上海浩洋生物科技有限公司
2010/7/9 8:53:48| Synonym: | Actinomycin C1, Actinomycin IV, Dactinomycin |
| CAS Number: | 50-76-0 |
| Linear Formula: | C62H86N12O16 |
| Molecular Weight: | 1255.42 |
| Beilstein Registry Number: | 605235 |
| EC Number: | 200-063-6 |
| MDL number: | MFCD00005033 |
| PubChem Substance ID: | 24890541 |
| Biochem/physiol Actions | An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Induces apoptosis. Potent antitumor agent. For cell culture applications, actinomycin D is used as a selection agent and is used in banding techniques to differentiate between different regions of chromosomes. |
| Caution | Hygroscopic and light sensitive. |
| biological source | from Streptomyces sp. |
| assay | ~98% （HPLC） |
| form | powder |
| color | red, powder |
| | red to orange |
| mp | 251-253 |
| solubility | DMSO: 1 mg/mL |
| | ethanol: soluble |
| storage temp. | 2-8°C |
| Personal Protective Equipment | Eyeshields , Faceshields , full-face particle respirator type N100 （US） , Gloves , respirator cartridge type N100 （US） , type P1 （EN143） respirator filter , type P3 （EN 143） respirator cartridges |
| Hazard Codes | T+ |
| Risk Statements | 28 |
| Safety Statements | 22-28-36/37-45 |
| RIDADR | UN3462 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | AU1575000 |
| 品名 | 产地 | 货号 | 规格 | 单价 | 备注 |
| Actinomycin D/放线菌素D/更生霉素 | Sigma | A1410 | 5MG | 询价 | 现货 |
| Actinomycin D/放线菌素D/更生霉素 | Sigma | A55051 | 5MG | 询价 | 现货 |
