上海浩洋生物科技有限公司
2010/7/12 15:06:26
Synonym: | Actinomycin C1, Actinomycin IV, Dactinomycin |
CAS Number: | 50-76-0 |
Linear Formula: | C62H86N12O16 |
Molecular Weight: | 1255.42 |
Beilstein Registry Number: | 605235 |
EC Number: | 200-063-6 |
MDL number: | MFCD00005033 |
PubChem Substance ID: | 24890541 |
Biochem/physiol Actions | An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Induces apoptosis. Potent antitumor agent. For cell culture applications, actinomycin D is used as a selection agent and is used in banding techniques to differentiate between different regions of chromosomes. |
Caution | Hygroscopic and light sensitive. |
biological source | from Streptomyces sp. |
assay | ~98% (HPLC) |
form | powder |
color | red, powder |
| red to orange |
mp | 251-253 |
solubility | DMSO: 1 mg/mL |
| ethanol: soluble |
storage temp. | 2-8°C |
Personal Protective Equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
Hazard Codes | T+ |
Risk Statements | 28 |
Safety Statements | 22-28-36/37-45 |
RIDADR | UN3462 6.1/PG 2 |
WGK Germany | 3 |
RTECS | AU1575000 |
品名 | 产地 | 货号 | 规格 | 单价 | 备注 |
Actinomycin D/放线菌素D/更生霉素 | Sigma | A1410 | 5MG | 询价 | 现货 |
Actinomycin D/放线菌素D/更生霉素 | Sigma | A55051 | 5MG | 询价 | 现货 |