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锌指蛋白300抗体
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产品编号bs-0628R
英文名称ZNF300
中文名称锌指蛋白300抗体
别 名Kruppel like zinc finger protein; Zinc finger protein 300; ZN300_HUMAN.
规格价格0.1ml/980元 购买 0.2ml/1580元 购买
说 明 书0.1ml 0.2ml
研究领域染色质和核信号 信号转导 转录调节因子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse,
产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量68kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ZNF300
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
生 产 商BIOSS
PubMedPubMed
锌指蛋白300抗体产品介绍background:
ZNF300 contains C2H2 (or Kruppel)-type zinc finger motifs that tetrahedrally coordinate zinc ions and form a protein structure that can bind DNA and regulate transcription (Gou et al.,2004 [PubMed 14746915]). ZNF300 belongs to the krueppel C2H2 type zinc finger protein family. It contains twelve C2H2 type zinc fingers and one KRAB domain. ZNF300 has a transcriptional repressor activity. Expressed mostly in heart, skeletal muscle and brain. Isoforms 1 and 2 are highly expressed in testis. There are three named isoforms.
Function:
Has a transcriptional repressor activity.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed mostly in heart, skeletal muscle and brain. Isoform 1 and isoform 2 are highly expressed in testis.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 12 C2H2-type zinc fingers.
Contains 1 KRAB domain.
SWISS:
Q96RE9
Gene ID:
91975
Database links:
Entrez Gene: 91975 Human
Omim: 612429 Human
SwissProt: Q96RE9 Human
Unigene: 134885 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ZNF300白血病相关性研究。
产品图片
Protein: line1, rat brain lysates, 30ug; line2, rat intestine lysates, 30ug;
Primary: Anti-ZNF300 (bs-0628R) at 1:200;
Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 3000;
ECL excitated the fluorescence;
Predicted band size : 66kD
Observed band size : 66kD
We are unsure as to the identity of these extra bands