Recombinant Human Epiregulin

92516ESRecombinant Human Epiregulin

参考价: ¥385

具体成交价以合同协议为准
2024-05-06 08:57:02
122
属性:
供货周期:现货;应用领域:医疗卫生,生物产业;
>
规格:
5 μg;
>
产品属性
供货周期
现货
应用领域
医疗卫生,生物产业
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Recombinant Human Epiregulin

参考价: ¥385

5 μg 385元 99 件可售
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翌圣生物科技(上海)股份有限公司

翌圣生物科技(上海)股份有限公司

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产品简介

Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as

详细介绍

Product Information

Product  Name

Cat#

Size

Recombinant Human Epiregulin Protein

92516ES08

5μg

92516ES50

5μg

92516ES60

100μg

92516ES76

500μg

 

Product Description

Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence.

 

Product Properties

Synonyms

EREG

Accession

O14944 

GeneID

2069

Source

E.coli-derived Human Epiregulin protein,Val60-Leu108.

Molecular Weight

Approximately 5.6 kDa.

AA Sequence

AVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS YA

Tag

None

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

> 97 % by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 2 ng/mL, corresponding to a specific activity of > 5.0 × 105 IU/mg.

Endotoxin

< 1.0 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at -20 to -80 for 1 year.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

  1. Avoid repeated freeze-thaw cycles.

  2. For your safety and health, please wear lab coats and disposable gloves for operation.

  3. For research use only.



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