Recombinant Mouse IL-1α

90139ESRecombinant Mouse IL-1α

参考价: ¥535

具体成交价以合同协议为准
2024-05-09 08:45:17
181
属性:
供货周期:现货;应用领域:医疗卫生,生物产业;
>
规格:
2 μg;
>
产品属性
供货周期
现货
应用领域
医疗卫生,生物产业
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Recombinant Mouse IL-1α

参考价: ¥535

2 μg 535元 20 件可售
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翌圣生物科技(上海)股份有限公司

翌圣生物科技(上海)股份有限公司

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产品简介

Interleukin-1 alpha (IL1a) is also known as IL-1A, IL1,and is a cytokine of the interleukin-1 family. Among various species, the amino acid sequence of mature IL-1 alpha is conserved 60% to 70% and hu

详细介绍

Product Information

Product Name

Cat#

Size

Recombinant Mouse IL-1α Protein

90139ES05

2 μg

90139ES10

10 μg

90139ES50

5μg

90139ES60

10μg

90139ES76

500 μg

 

Product Description

Interleukin-1 alpha (IL1a) is also known as IL-1A, IL1,and is a cytokine of the interleukin-1 family. Among various species, the amino acid sequence of mature IL-1 alpha is conserved 60% to 70% and human IL-1 has been found to be biologically active on murine cell lines. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. IL-1 is a major immunoregulatory/proinflammatory cytokine which also affects fibroblast proliferation and function and therefore it was of interest to investigate whether its constitutive expression influences the in vivo tumorigenic potential of transformed fibroblastoid cell lines.

 

Product Properties

Synonyms

Interleukin-1 alpha, IL-1α, BAF, IL-1F1, LAF, LEMpreinterleukin 1 alpha, pro-interleukin-1-alpha

Accession

 Q3U0Y6

GeneID

16175

Source

E.coli-derived mouse IL-1alpha proteinSer115-Ala270.

Molecular Weight

Approximately 17.9 kDa.

AA Sequence

SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS

Tag

None

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

> 97% by SDS-PAGE and HPLC analyses.

Biological Activity

The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 2 pg/mL, corresponding to a specific activity of > 5.0 × 108 IU/mg. Fully biologically active when compared to standard.

Endotoxin

< 1.0 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20. Further dilutions should be made in appropriate buffered solutions.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at -20 to -80 for 1 year.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

  1. Avoid repeated freeze-thaw cycles.

  2. For your safety and health, please wear lab coats and disposable gloves for operation.

  3. For research use only!

HB240321

 

 

 

 

 


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