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LONZA CC-3198 HCM肝细胞培养基 现货供应
面议LONZA代理 CC-3198 HCM肝细胞培养基 优势
面议LONZA CC-3198 HCM肝细胞培养基 现货
面议Corning 88-591-CM细胞培养基 优化细胞表型
面议Lifeline CM-0045 大豆酪蛋白胨培养基 TSB
面议Lifeline LL-0001 成纤维细胞培养基 无血清
面议Lifeline LL-0001 成纤维无血清培养基套装
面议Lifeline FibroLife 成纤维无血清培养基
面议FibroLife 成纤维无血清培养基套装 LL-0001
面议Gibco™ Advanced™培养基 减血清 现货
面议Gibco™ Advanced™培养基 现货折扣
面议12634010 Advanced DMEM/F-12 培养基
面议产品英文名称: GDC-0449, SMO Antagonist
产品中文名称: GDC-0449, SMO 拮抗剂
GDC-0449, SMO Antagonist 产品英文简述:
GDC-0449 (Vismodegib): A potent antagonist of SMO (smoothened). This small molecule compound is a hedgehog pathway inhibitor by directly binding to SMO. This molecule has been developed by Genentech for clinical application against hedgehog-dependent cancers.
Purity: Greater than 99% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: In a cell-based assay measuring the activation of the Gli-1 reporter gene, this compound gives IC50 of 5-20 nM.
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