产品英文名称: CHIR99021

产品中文名称: CHIR99021

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CHIR99021产品英文简述:
CHIR99021 （CT99021） is a glycogen synthase kinase 3β （GSK3β） inhibitor with IC50 less than 10 nM. Compared to other GSK-3 inhibitors, CHIR-99201 does not exhibit cross-reactivity against cyclin-dependent kinases （CDKs） with 350-fold selectivity toward GSK-3β compared to CDKs .
Ref: Tighe A et al. BMC Cell Biol. 2007 Aug 14;8:34

Purity: Greater than 99% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: In a cell-based assay measuring the activation of the TCF reporter gene, this compound gives EC50 of 50 nM.

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