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康宁 88-591-CM无血清细胞培养基 买五送一
面议康宁CORNING Matrigel 基质胶 现货折扣
面议356234 corning Matrigel基质胶 康宁代理
面议Takara GT-T551H3 淋巴细胞无血清培养基H3
面议C3620-0500 VivaCell 羊水细胞培养基 现货
面议VivaCell羊水细胞培养基AmoioType-1 Medium
面议VivaCell C3620-0100 Bio-AMF-2 培养基
面议LL-0023 Lifeline代理 气道上皮细胞培养基
面议Lifeline LL-0023 气道上皮细胞培养基 现货
面议Lifeline LL-0023 气道上皮细胞培养基套装
面议Lifeline代理 气道上皮细胞培养套装 现货
面议lifeline LL-0003 VEGF内皮细胞培养基供应
面议产品英文名称: GDC-0449, SMO Antagonist
产品中文名称: GDC-0449, SMO 拮抗剂
GDC-0449, SMO Antagonist 产品英文简述:
GDC-0449 (Vismodegib): A potent antagonist of SMO (smoothened). This small molecule compound is a hedgehog pathway inhibitor by directly binding to SMO. This molecule has been developed by Genentech for clinical application against hedgehog-dependent cancers.
Purity: Greater than 99% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: In a cell-based assay measuring the activation of the Gli-1 reporter gene, this compound gives IC50 of 5-20 nM.
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