BPS Bioscience的蛋白酶筛选和检测服务

BPS Bioscience的蛋白酶筛选和检测服务

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2023-12-19 23:23:59
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BPS Bioscience Inc.

BPS Bioscience Inc.

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提供商:BPSBioscience服务名称:BPSBioscience的蛋白酶筛选和检测服务Accelerateyourdrugdiscoveryprogramwith ProteaseScreeningandProfilingServices fromBPSBioscience,Inc

详细介绍

Accelerate your drug discovery program with Protease Screening and Profiling Services from BPS Bioscience, Inc. Trust us to provide you with high quality data with fast turnaround time. Our team of experts along with our broad services portfolio makes it easy to:

  • Screen for inhibitors/targets using our panel of many different assays including Cathepsins, Caspases, Dipeptidyl Peptidases (DPPs), Deubiquitinases, and other Proteases

  • Select from IC50 determination and single point concentrations

  • Receive data within days of compound submission

  • Perform follow-up studies using the same proteins manufactured in-house

  • Get questions answered or project guidance in a time-efficient manner

    图片

Biochemical Assays:

Aspartic ProteasesCysteine ProteasesMetalloproteasesSerine Proteases
BACE1SARS-CoV-1 3C-like Protease (3CL)ADAM17CLP
Caspase-3SARS-CoV-2 3C-like Protease (3CL)MMP1DPP3
Caspase-6SARS-CoV-2 Papain-like Protease (PLPro)MMP2DPP4
Caspase-7A20MMP3DPP7
Caspase-8Ataxin-3MMP7DPP8
Caspase-9Cathepsin BMMP8DPP9
Renin, activatedCathepsin FMMP9 (Q279R)FAP
Cathepsin LMMP10Furin
Cathepsin SMMP11HCV1a (D168V)
Cathepsin VMMP12HCV1b
MALT1MMP13HCV1b (D168V)
OTUD6BcMMP14HCV1b (R155K)
UCHL1 HCV1b (R155Q)
UCHL3 HCV2a
USP2 POP
USP5 Protein C, activated
USP7 TMPRSS2
USP8
USP10
USP14

Note: Not all targets will have a commercially available reference control. Please inquire with our team if you need to furnish your own controls for specific targets.

Protease signaling pathways regulate a wide range of vital physiological processes, including digestion of food, lysosome and proteasome degradation, apoptosis, blood coagulation, and cell cycle regulation.

The dysregulation of protease activity can lead to pathologies such as arthritis and inflammatory diseases,cardiovascular disorders, cancer, osteoporosis, Alzheimer’s, and other neurological disorders. Several small molecule, protease inhibitor drugs are already on the market and many more are in development.

如果您需要了解更多关于我们的服务的信息,请联系info。

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