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ATAT1, GST-tag Recombinant
面议
ATF2, GST-Tag Recombinant
面议
GCN5 (727-837), His-tag Recombinant
面议
GCN5 (KAT2A), FLAG-tag Recombinant
面议
p300 (KAT3B), His-GST-tag Recombinant
面议
ACHE, His-Tag Recombinant
面议
APAF1, His-tag, FLAG-tag Recombinant
面议
BCL-2, His-Tag Recombinant
面议
BCL2A1, His-Tag Recombinant
面议
BCL2L10, His-Tag Recombinant
面议
Caspase6, His-tag Recombinant
面议
Caspase7, His-tag Recombinant
面议A-769662 is a potent, reversible activator of AMP-activated protein kinase (AMPK). AMPK is an αβγ heterotrimer and plays an important role in regulating cellular and whole-body metabolism. A-769662 only activates AMPK heterotrimers containing the β1 subunit. A-769662 activates AMPK through the β subunit carbohydrate-binding module and the γ subunit but not the AMP-binding sites. A-769662 stimulated partially purified rat liver AMPK with an EC50 of 0.8 µM and inhibited fatty acid synthesis in primary rat hepatocytes with an IC50 of 3.2 µM.
