Recombinant human WIF1
WIF-1; wif1; WIF1_HUMAN; Wnt Inhibitory Factor 1.
浓度：1mg/ ml
来源：Recombinant Human
纯度：≥95% SDS-PAGE
表达系统：HEK 293 cells
标签：His tag C-Terminus
蛋白长度：Full length protein
内毒素水平：<1.000 Eu/µg
纯化方法：HPLC
应用：SDS-PAGE，Western blot，ELISA
Biological activity,immunology research
保存：-20℃
保质期：1年
The Wnt genes are a group of conserved, Cysteine-rich, secreted glycoproteins that are required for numerous developmental processes including embryogenesis, asymmetric cell division and central nervous system (CNS) patterning. Wnt association with the transmembrane spanning receptor frizzled activates dishevelled, which downregulates glycogen synthase kinase (GSK) through serine phosphorylation. Reduced levels of active GSK causes accumulation of b-catenin and subsequent regulation of developmentally significant Wnt target genes. Wnt antagonists such as dickkopf (Dkk), frizzled-related protein (sFRP) and Wnt inhibitory factor-1 (WIF-1), are necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes. WIF-1 is a 379-amino acid secreted protein that contains an N-terminal signal sequence, a 150-amino acid WIF domain, five epidermal growth factor-like repeats and a 45-amino acid C-terminal hydrophilic domain.
产品名称：Rabbit Anti-WIF1 antibody
Rabbit Anti-WIF1
别名：WIF-1; wif1; WIF1_HUMAN; Wnt Inhibitory Factor 1.
来源：Rabbit
克隆类型：Polyclonal
浓度：1mg/ml
亚型：IgG
反应：(predicted: Human,Mouse,Rat,Pig,Cow,Chicken,Dog,Horse)
应用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
理论分子量：39kDa
免疫原：KLH conjugated synthetic peptide derived from human WIF1
保存：-20℃
保质期：1年
产品名称：Anti-WIF1 antibody
Mouse Anti-WIF1
别名：WIF-1; wif1; WIF1_HUMAN; Wnt Inhibitory Factor 1.
来源：Mouse
克隆类型：Monoclonal
浓度：1mg/ml
亚型：IgG
反应：Human
应用：WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反应: Human
理论分子量：39kDa
免疫原：KLH conjugated synthetic peptide derived from human WIF1
保存：-20℃
保质期：1年
The Wnt genes are a group of conserved, Cysteine-rich, secreted glycoproteins that are required for numerous developmental processes including embryogenesis, asymmetric cell division and central nervous system (CNS) patterning. Wnt association with the transmembrane spanning receptor frizzled activates dishevelled, which downregulates glycogen synthase kinase (GSK) through serine phosphorylation. Reduced levels of active GSK causes accumulation of b-catenin and subsequent regulation of developmentally significant Wnt target genes. Wnt antagonists such as dickkopf (Dkk), frizzled-related protein (sFRP) and Wnt inhibitory factor-1 (WIF-1), are necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes. WIF-1 is a 379-amino acid secreted protein that contains an N-terminal signal sequence, a 150-amino acid WIF domain, five epidermal growth factor-like repeats and a 45-amino acid C-terminal hydrophilic domain.
