技术文章

VGAT抗原,氨基丁酸转运蛋白VGAT抗原

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2024/11/27 10:35:03

Recombinant human VGAT   

VGAT; bA122O1.1; GABA and glycine transporter; hVIAAT; SLC32A 1; solute carrier family 32 (GABA vesicular transporter) member 1; Solute carrier family 32 member 1; Vesicular GABA Amino Acid Transporter; Vesicular GABA transporter; Vesicular inhibitory amino acid transporter; VGAT; VIAAT; VIAAT_HUMAN.    

浓度:1mg/ ml

来源:Recombinant Human

纯度:≥95% SDS-PAGE

表达系统:Yeast

标签:His tag

蛋白长度:Full length protein

内毒素水平:<1.000 Eu/µg

纯化方法:HPLC

应用:SDS-PAGE,Western blot,ELISA

Biological activity,immunology research

保存:-20℃

保质期:1年

Synaptic transmission involves the controlled exocytosis of vesicles containing specific neurotransmitters. Usually, neurotransmitters are synthesized in the cytoplasm of the cell and must be transported into synaptic vesicles for release. The vesicular GABA transporter (VGAT) is responsible for loading gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, from neuronal cytoplasm into synaptic vesicles and is expressed only in the nerve endings of inhibitory neurons that contain GABA and/or glycine. During neocortical development, VGAT expression barely precedes the maturation of inhibitory synaptogenesis, suggesting that it may contribute to the development of neocortical GABAergic circuitry. VGAT may also play a role in epileptogenesis and the recovery mechanisms that occur after a spontaneous seizure


产品名称:Rabbit Anti-VGAT  antibody

Rabbit Anti-VGAT  

别名:VGAT; bA122O1.1; GABA and glycine transporter; hVIAAT; SLC32A 1; solute carrier family 32 (GABA vesicular transporter) member 1; Solute carrier family 32 member 1; Vesicular GABA Amino Acid Transporter; Vesicular GABA transporter; Vesicular inhibitory amino acid transporter; VGAT; VIAAT; VIAAT_HUMAN.     

来源:Rabbit

克隆类型:Polyclonal

浓度:1mg/ml

亚型:IgG

应用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反应:(predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow)

理论分子量:57kDa

免疫原:KLH conjugated synthetic peptide derived from human VGAT

保存:-20
保质期:1

 

单克隆抗体

产品名称:Anti-VGAT antibody

Mouse Anti-VGAT 

别名:VGAT; bA122O1.1; GABA and glycine transporter; hVIAAT; SLC32A 1; solute carrier family 32 (GABA vesicular transporter) member 1; Solute carrier family 32 member 1; Vesicular GABA Amino Acid Transporter; Vesicular GABA transporter; Vesicular inhibitory amino acid transporter; VGAT; VIAAT; VIAAT_HUMAN.    

来源:Mouse

克隆类型:Monoclonal

浓度:1mg/ml

亚型:IgG

应用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反应: Human

理论分子量:57kDa

免疫原:KLH conjugated synthetic peptide derived from human VGAT

保存:-20
保质期:1

Synaptic transmission involves the controlled exocytosis of vesicles containing specific neurotransmitters. Usually, neurotransmitters are synthesized in the cytoplasm of the cell and must be transported into synaptic vesicles for release. The vesicular GABA transporter (VGAT) is responsible for loading gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, from neuronal cytoplasm into synaptic vesicles and is expressed only in the nerve endings of inhibitory neurons that contain GABA and/or glycine. During neocortical development, VGAT expression barely precedes the maturation of inhibitory synaptogenesis, suggesting that it may contribute to the development of neocortical GABAergic circuitry. VGAT may also play a role in epileptogenesis and the recovery mechanisms that occur after a spontaneous seizure




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